ENZYME entry: EC 2.4.99.1
| Accepted Name |
|---|
| Beta-galactoside alpha-2,6-sialyltransferase.
|
| Alternative Name(s) |
|---|
| Beta-galactosamide alpha-2,6-sialyltransferase. |
| CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase. |
| Reaction catalysed |
|---|
| CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine <=> CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine |
| Comment(s) |
|---|
| The terminal beta-D-galactosyl residue of the oligosaccharide of
glycoproteins, as well as lactose, can act as acceptor.
|
| Cross-references |
|---|
| BRENDA | 2.4.99.1 |
| EC2PDB | 2.4.99.1 |
| ExplorEnz | 2.4.99.1 |
| PRIAM enzyme-specific profiles | 2.4.99.1 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.4.99.1 |
| IUBMB Enzyme Nomenclature | 2.4.99.1 |
| IntEnz | 2.4.99.1 |
| MEDLINE | Find literature relating to 2.4.99.1 |
| MetaCyc | 2.4.99.1 |
| UniProtKB/Swiss-Prot |
| Q92182, SIAT1_CHICK; | P15907, SIAT1_HUMAN; | Q64685, SIAT1_MOUSE; |
| P13721, SIAT1_RAT; | A5D7T4, SIAT2_BOVIN; | Q701R0, SIAT2_CHICK; |
| Q701R2, SIAT2_DANRE; | Q96JF0, SIAT2_HUMAN; | Q76K27, SIAT2_MOUSE; |
| Q5K027, SIAT2_ORYLA; | Q701R4, SIAT2_PANTR; | Q701R3, SIAT2_RAT; |
| Q5QQ37, SIAT2_TAKRU; | Q701R1, SIAT2_XENTR; |
|
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