ENZYME

ENZYME entry: EC 2.4.99.7

Accepted Name

Alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetylgalactosaminide 6-alpha-sialyltransferase.

Alternative Name(s)

Alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase.

Cytidine monophosphoacetylneuraminate-(alpha-N-acetylneuraminyl-2,3-beta- galactosyl-1,3)-N-acetylgalactosaminide-alpha-2,6-sialyltransferase.

NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase.

Sialyltransferase.

Sialyltransferase 3C.

Sialyltransferase 7D.

ST6GALNAC.

Reaction catalysed

CMP-N-acetylneuraminate + N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R <=> CMP + N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-(N-acetyl-alpha-neuraminyl-(2->6))-N-acetyl-D-galactosaminyl-R

Comment(s)

Attaches N-acetylneuraminic acid in alpha-2,6-linkage to N-acetyl- galactosamine only when present in the structure of alpha-N-acetyl- neuraminyl-(2->3)-beta-galactosyl-(1->3)-N-acetylgalactosaminyl-R, where R may be protein or p-nitrophenol.
Not identical with EC 2.4.99.3.

Cross-references

BRENDA

2.4.99.7

EC2PDB

2.4.99.7

ExplorEnz

2.4.99.7

PRIAM enzyme-specific profiles

2.4.99.7

KEGG Ligand Database for Enzyme Nomenclature

2.4.99.7

IUBMB Enzyme Nomenclature