ENZYME entry: EC 2.5.1.10

Accepted Name
(2E,6E)-farnesyl diphosphate synthase.
Alternative Name(s)
Farnesyl pyrophosphate synthetase.
Farnesyl-diphosphate synthase.
FPP synthetase.
Geranyltranstransferase.
Reaction catalysed
Geranyl diphosphate + isopentenyl diphosphate <=> diphosphate + (2E,6E)-farnesyl diphosphate
Comment(s)
  • Some forms of this enzyme will also use dimethylallyl diphosphate as a substrate.
  • The enzyme will not accept larger prenyl diphosphates as efficient donors.
Cross-references
PROSITEPDOC00407
BRENDA2.5.1.10
EC2PDB2.5.1.10
ExplorEnz2.5.1.10
PRIAM enzyme-specific profiles2.5.1.10
KEGG Ligand Database for Enzyme Nomenclature2.5.1.10
IUBMB Enzyme Nomenclature2.5.1.10
IntEnz2.5.1.10
MEDLINEFind literature relating to 2.5.1.10
MetaCyc2.5.1.10
UniProtKB/Swiss-Prot
P0A5H9, EFPP_MYCBO;  P9WKH0, EFPP_MYCTO;  P9WKH1, EFPP_MYCTU;  
Q09152, FPPS1_ARATH;  Q7XYS9, FPPS1_ARTSI;  P49351, FPPS1_LUPAL;  
O24241, FPPS1_PARAR;  Q43315, FPPS2_ARATH;  Q7XYT0, FPPS2_ARTSI;  
P49352, FPPS2_LUPAL;  O24242, FPPS2_PARAR;  P49350, FPPS_ARTAN;  
Q8WMY2, FPPS_BOVIN;  P08836, FPPS_CHICK;  Q92235, FPPS_GIBFU;  
O64905, FPPS_HELAN;  P14324, FPPS_HUMAN;  P49349, FPPS_KLULA;  
P49353, FPPS_MAIZE;  Q920E5, FPPS_MOUSE;  Q92250, FPPS_NEUCR;  
P05369, FPPS_RAT;  O14230, FPPS_SCHPO;  P08524, FPPS_YEAST;  
Q9NH03, FPS_DICDI;  P34802, GGPP1_ARATH;  O04046, GGPP2_ARATH;  
Q9LUD9, GGPP3_ARATH;  Q9SLG2, GGPP4_ARATH;  O22043, GGPP6_ARATH;  
Q9ZU77, GGPP7_ARATH;  Q9LRR0, GGPP8_ARATH;  Q9LUE1, GGPP9_ARATH;  
Q9LJY2, GGPPA_ARATH;  Q9LIA0, GGPPB_ARATH;  Q9LHR4, GGPPC_ARATH;  
Q758K0, GGPPS_ASHGO;  P56966, GGPPS_BOVIN;  P80042, GGPPS_CAPAN;  
Q42698, GGPPS_CATRO;  Q54BK1, GGPPS_DICDI;  Q92236, GGPPS_GIBFU;  
Q94ID7, GGPPS_HEVBR;  O95749, GGPPS_HUMAN;  Q9WTN0, GGPPS_MOUSE;  
Q9P885, GGPPS_MUCCL;  P24322, GGPPS_NEUCR;  Q6F596, GGPPS_RAT;  
O59703, GGPPS_SCHPO;  Q43133, GGPPS_SINAL;  Q12051, GGPPS_YEAST;  
B2DBE8, GGS1_PHOAM;  B2DBE9, GGS4_PHOAM;  O66952, ISPA_AQUAE;  
P54383, ISPA_BACSU;  Q45220, ISPA_BRADU;  P57537, ISPA_BUCAI;  
Q8K9A0, ISPA_BUCAP;  P22939, ISPA_ECOLI;  Q08291, ISPA_GEOSE;  
P45204, ISPA_HAEIN;  O66126, ISPA_MICLU;  P55539, ISPA_RHISN;  
Q65164, TPRT_ASFB7;  P0C9E2, TPRT_ASFK5;  Q8V9T7, TPRT_ASFM2;  
P0C9E0, TPRT_ASFP4;  P0C9E1, TPRT_ASFWA;  Q55EU7, Y8742_DICDI;  
Q54XP1, Y8823_DICDI;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
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