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ENZYME

ENZYME entry: EC 2.5.1.106

Accepted Name
tryprostatin B synthase
Alternative Name(s)
brevianamide F prenyltransferase
Reaction catalysed
brevianamide F + dimethylallyl diphosphate <=> diphosphate + tryprostatin B
Comment(s)
  • The enzyme from the fungus Aspergillus fumigatus can also prenylate other tryptophan-containing cyclic dipeptides.
  • Prenylation occurs mainly at C-2, but also at C-3.
  • Involved in the biosynthetic pathways of several indole alkaloids such as tryprostatins, cyclotryprostatins, spirotryprostatins, fumitremorgins and verruculogen.
Cross-references
BRENDA2.5.1.106
EC2PDB2.5.1.106
ExplorEnz2.5.1.106
PRIAM enzyme-specific profiles2.5.1.106
KEGG Ligand Database for Enzyme Nomenclature2.5.1.106
IUBMB Enzyme Nomenclature2.5.1.106
IntEnz2.5.1.106
MEDLINEFind literature relating to 2.5.1.106
MetaCyc2.5.1.106
Rhea expert-curated reactions2.5.1.106
UniProtKB/Swiss-Prot
B9WZX3, FTMB_ASPFMQ4WAW7, FTMB_ASPFUA1DA62, FTMB_NEOFI

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