ID   2.5.1.108
DE   2-(3-amino-3-carboxypropyl)histidine synthase.
CA   L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine =
CA   2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor
CA   2] + H(+) + S-methyl-5'-thioadenosine.
CC   -!- Modifies a histidine residue of the translation elongation factor 2
CC       (EF2) via a 3-amino-3-carboxypropyl radical.
CC   -!- The enzyme is present in archae and eukaryotes but not in eubacteria.
CC   -!- Part of diphthamide biosynthesis.
CC   -!- Formerly EC 2.5.1.n7.
DR   Q4X0S7, DPH1_ASPFU ;  Q3SYT1, DPH1_BOVIN ;  P49958, DPH1_CAEEL ;
DR   Q59MG1, DPH1_CANAL ;  Q6FTG1, DPH1_CANGA ;  Q5ZHX9, DPH1_CHICK ;
DR   A0A8C2MDK8, DPH1_CRIGR ;  P0CN19, DPH1_CRYNB ;  P0CN18, DPH1_CRYNJ ;
DR   Q567W6, DPH1_DANRE ;  Q6BPU5, DPH1_DEBHA ;  Q54PW5, DPH1_DICDI ;
DR   Q5AZJ7, DPH1_EMENI ;  Q8SUZ5, DPH1_ENCCU ;  Q75AZ9, DPH1_EREGS ;
DR   Q4IQ72, DPH1_GIBZE ;  Q9BZG8, DPH1_HUMAN ;  Q6CLC9, DPH1_KLULA ;
DR   Q5NCQ5, DPH1_MOUSE ;  A7SLX5, DPH1_NEMVE ;  Q7SC98, DPH1_NEUCR ;
DR   Q3T7C9, DPH1_PENVA ;  O59713, DPH1_SCHPO ;  Q4PA25, DPH1_USTMA ;
DR   Q6GPQ5, DPH1_XENLA ;  Q6C0S8, DPH1_YARLI ;  P40487, DPH1_YEAST ;
DR   Q57907, DPH2_METJA ;  O58832, DPH2_PYRHO ;
//