ENZYME entry: EC 2.5.1.119

Accepted Name
Beta-(isoxazolin-5-on-4-yl)-L-alanine synthase.
Reaction catalysed
O(3)-acetyl-L-serine + isoxazolin-5-one <=> 3-(5-oxoisoxazolin-4-yl)-L-alanine + acetate
Comment(s)
  • 3-(5-oxoisoxazolin-4-yl)-L-alanine is an antifungal antibiotic produced by the bacterium Streptomyces platensis.
  • The enzymes from the plants Lathyrus odoratus (sweet pea), L.sativus (grass pea) and Citrullus vulgaris (watermelon) that catalyze EC 2.5.1.118 also catalyze this reaction in vitro, but not in vivo.
  • Closely related and possibly identical to EC 2.5.1.47 and EC 2.5.1.51.
Cross-references
BRENDA2.5.1.119
EC2PDB2.5.1.119
ExplorEnz2.5.1.119
PRIAM enzyme-specific profiles2.5.1.119
KEGG Ligand Database for Enzyme Nomenclature2.5.1.119
IUBMB Enzyme Nomenclature2.5.1.119
IntEnz2.5.1.119
MEDLINEFind literature relating to 2.5.1.119
MetaCyc2.5.1.119

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
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