Expasy logo

ENZYME

ENZYME entry: EC 2.5.1.143

Accepted Name
pyridinium-3,5-biscarboxylic acid mononucleotide synthase
Alternative Name(s)
NaAD carboxylase/hydrolase
nicotinic acid adenine dinucleotide carboxylase/hydrolase
P2CMN synthase
Reaction catalysed
deamido-NAD(+) + hydrogencarbonate <=> AMP + 2 H(+) + pyridinium-3,5-dicarboxylate mononucleotide
Comment(s)
  • This enzyme, found in the bacterium Lactobacillus plantarum, is involved in the biosynthesis of a nickel-pincer cofactor.
  • It carboxylates the pyridinium ring of deamido-NAD(+) and cleaves the phosphoanhydride bond to release AMP and generate pyridinium-3,5- biscarboxylic acid mononucleotide (P2CMN).
Cross-references
BRENDA2.5.1.143
EC2PDB2.5.1.143
ExplorEnz2.5.1.143
PRIAM enzyme-specific profiles2.5.1.143
KEGG Ligand Database for Enzyme Nomenclature2.5.1.143
IUBMB Enzyme Nomenclature2.5.1.143
IntEnz2.5.1.143
MEDLINEFind literature relating to 2.5.1.143
MetaCyc2.5.1.143
Rhea expert-curated reactions2.5.1.143
UniProtKB/Swiss-Prot
F9UST0, LARB_LACPL

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-