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ENZYME

ENZYME entry: EC 2.5.1.155

Accepted Name
phosphoglycerol geranylfarnesyltransferase
Alternative Name(s)
GFGP synthase
Reaction catalysed
(2E,6E,10E,14E)-geranylfarnesyl diphosphate + sn-glycerol 1-phosphate <=> diphosphate + sn-3-(O-farnesylgeranyl)glycerol 1-phosphate
Comment(s)
  • The enzyme, characterized from the archaeon Aeropyrum pernix, catalyzes the first pathway-specific step in the biosynthesis of the core membrane C25,C25-diether lipids in some archaea.
  • It does not act on geranylgeranyl diphosphate. cf. EC 2.5.1.41.
Cross-references
BRENDA2.5.1.155
EC2PDB2.5.1.155
ExplorEnz2.5.1.155
PRIAM enzyme-specific profiles2.5.1.155
KEGG Ligand Database for Enzyme Nomenclature2.5.1.155
IUBMB Enzyme Nomenclature2.5.1.155
IntEnz2.5.1.155
MEDLINEFind literature relating to 2.5.1.155
MetaCyc2.5.1.155
Rhea expert-curated reactions2.5.1.155

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-