ENZYME entry: EC 2.5.1.29

Accepted Name
Geranylgeranyl diphosphate synthase.
Alternative Name(s)
Farnesyltransferase.
Farnesyltranstransferase.
Geranylgeranyl pyrophosphate synthase.
Geranylgeranyl pyrophosphate synthetase.
Geranylgeranyl-diphosphate synthase.
Geranylgeranyl-PP synthetase.
Reaction catalysed
(2E,6E)-farnesyl diphosphate + isopentenyl diphosphate <=> diphosphate + geranylgeranyl diphosphate
Comment(s)
Some forms of this enzyme will also use geranyl diphosphate and dimethylallyl diphosphate as donors; it will not use larger prenyl diphosphates as efficient donors.
Cross-references
PROSITEPDOC00407
BRENDA2.5.1.29
EC2PDB2.5.1.29
ExplorEnz2.5.1.29
PRIAM enzyme-specific profiles2.5.1.29
KEGG Ligand Database for Enzyme Nomenclature2.5.1.29
IUBMB Enzyme Nomenclature2.5.1.29
IntEnz2.5.1.29
MEDLINEFind literature relating to 2.5.1.29
MetaCyc2.5.1.29
UniProtKB/Swiss-Prot
P48368, CRTE_CYAPA;  P22873, CRTE_ESCVU;  P21684, CRTE_PANAN;  
P17060, CRTE_RHOCB;  P54976, CRTE_RHOS4;  C9K2Q3, FUSS_ALTBR;  
A2PZA5, FUSS_PHOAM;  P34802, GGPP1_ARATH;  O04046, GGPP2_ARATH;  
Q9LUD9, GGPP3_ARATH;  Q9SLG2, GGPP4_ARATH;  O22043, GGPP6_ARATH;  
Q9ZU77, GGPP7_ARATH;  Q9LRR0, GGPP8_ARATH;  Q9LUE1, GGPP9_ARATH;  
Q9LJY2, GGPPA_ARATH;  Q9LIA0, GGPPB_ARATH;  Q9LHR4, GGPPC_ARATH;  
Q758K0, GGPPS_ASHGO;  P56966, GGPPS_BOVIN;  P80042, GGPPS_CAPAN;  
Q42698, GGPPS_CATRO;  Q54BK1, GGPPS_DICDI;  Q92236, GGPPS_GIBFU;  
Q94ID7, GGPPS_HEVBR;  O95749, GGPPS_HUMAN;  Q9WTN0, GGPPS_MOUSE;  
Q9P885, GGPPS_MUCCL;  P24322, GGPPS_NEUCR;  Q6F596, GGPPS_RAT;  
O59703, GGPPS_SCHPO;  Q43133, GGPPS_SINAL;  Q12051, GGPPS_YEAST;  
Q8PW34, GGPP_METMA;  P39464, GGPS_SULAC;  P95999, GGPS_SULSO;  
B2DBE8, GGS1_PHOAM;  B2DBE9, GGS4_PHOAM;  Q65164, TPRT_ASFB7;  
P0C9E2, TPRT_ASFK5;  Q8V9T7, TPRT_ASFM2;  P0C9E0, TPRT_ASFP4;  
P0C9E1, TPRT_ASFWA;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
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