ID   2.5.1.42
DE   geranylgeranylglycerol-phosphate geranylgeranyltransferase.
AN   (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase.
AN   DGGGPS.
AN   DGGGP synthase.
CA   (2E,6E,10E)-geranylgeranyl diphosphate + sn-3-O-(geranylgeranyl)glycerol
CA   1-phosphate = 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate +
CA   diphosphate.
CC   -!- Carries out the second prenyltransfer reaction involved in the
CC       formation of polar membrane lipids in archaea.
CC   -!- 4-Hydroxybenzoate, 1,4-dihydroxy 2-naphthoate, homogentisate and
CC       alpha-glycerophosphate cannot act as prenyl-acceptor substrates.
CC   -!- The other enzymes involved in the biosynthesis of polar lipids in
CC       archaea are EC 1.1.1.261, EC 2.5.1.41, which, together with this
CC       enzyme, alkylates the hydroxy groups of glycerol 1-phosphate to yield
CC       unsaturated archaetidic acid, which is acted upon by EC 2.7.7.67 to
CC       form CDP-unsaturated archaeol.
CC   -!- The final step in the pathway involves the addition of L-serine, with
CC       concomitant removal of CMP, leading to the production of unsaturated
CC       archaetidylserine.
DR   O29843, DGGGP_ARCFU;  B0R3S1, DGGGP_HALS3;  Q9HRP0, DGGGP_HALSA;
DR   Q18J00, DGGGP_HALWD;  A2BIU7, DGGGP_HYPBU;  A8A9J7, DGGGP_IGNH4;
DR   B1L6Z7, DGGGP_KORCO;  A6UVU6, DGGGP_META3;  Q8TS44, DGGGP_METAC;
DR   A7I9E7, DGGGP_METB6;  Q46BD9, DGGGP_METBF;  Q12VF3, DGGGP_METBU;
DR   Q2FN44, DGGGP_METHJ;  Q57727, DGGGP_METJA;  Q8TWS9, DGGGP_METKA;
DR   A2SRL0, DGGGP_METLZ;  A4G0P3, DGGGP_METM5;  A9A8Y7, DGGGP_METM6;
DR   A6VHU1, DGGGP_METM7;  Q8PV96, DGGGP_METMA;  A3CW74, DGGGP_METMJ;
DR   Q6LWN2, DGGGP_METMP;  A5ULR8, DGGGP_METS3;  A4YI21, DGGGP_METS5;
DR   Q2NGM1, DGGGP_METST;  O27170, DGGGP_METTH;  A0B8A0, DGGGP_METTP;
DR   A6UQV8, DGGGP_METVS;  Q3INH7, DGGGP_NATPD;  Q9V2P5, DGGGP_PYRAB;
DR   Q8TZM7, DGGGP_PYRFU;  O57753, DGGGP_PYRHO;  Q9UWY6, DGGGP_SACS2;
DR   Q4J8K2, DGGGP_SULAC;  Q971A3, DGGGP_SULTO;  C5A1J7, DGGGP_THEGJ;
DR   Q5JDN5, DGGGP_THEKO;  B6YW76, DGGGP_THEON;  A1S066, DGGGP_THEPD;
DR   C6A2C9, DGGGP_THESM;
//