ID   2.5.1.48
DE   Cystathionine gamma-synthase.
AN   Cystathionine synthase.
AN   Cystathionine synthetase.
AN   Homoserine O-transsuccinylase.
AN   Homoserine transsuccinylase.
AN   O-succinyl-L-homoserine succinate-lyase (adding cysteine).
AN   O-succinylhomoserine (thiol)-lyase.
AN   O-succinylhomoserine synthase.
AN   O-succinylhomoserine synthetase.
CA   O(4)-succinyl-L-homoserine + L-cysteine = L-cystathionine + succinate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Also reacts with H(2)S and methanethiol as replacing agents,
CC       producing homocysteine and methionine, respectively.
CC   -!- In the absence of thiol, can also catalyze beta,gamma-elimination to
CC       form 2-oxobutanoate, succinate and ammonia.
CC   -!- Formerly EC 4.2.99.9.
PR   PROSITE; PDOC00677;
DR   P38675, MET7_NEUCR ;  O74314, MET7_SCHPO ;  P47164, MET7_YEAST ;
DR   P55217, METB_ARATH ;  P00935, METB_ECOLI ;  P44502, METB_HAEIN ;
DR   Q9ZMW7, METB_HELPJ ;  Q1M0P5, METB_HELPX ;  P56069, METB_HELPY ;
DR   P24601, METB_HERAU ;  P66876, METB_MYCBO ;  P46807, METB_MYCLE ;
DR   P66875, METB_MYCTU ;  Q12198, METW_YEAST ;  Q04533, METX_YEAST ;
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