ENZYME entry: EC 2.5.1.68

Accepted Name
(2Z,6E)-farnesyl diphosphate synthase.
Alternative Name(s)
(Z)-farnesyl diphosphate synthase.
Z-farnesyl diphosphate synthase.
Reaction catalysed
Geranyl diphosphate + isopentenyl diphosphate <=> diphosphate + (2Z,6E)-farnesyl diphosphate
Cofactor(s)
Mn(2+) or Mg(2+).
Comment(s)
  • The product of this reaction is an intermediate in the synthesis of decaprenyl phosphate, which plays a central role in the biosynthesis of most features of the mycobacterial cell wall, including peptidoglycan, linker unit galactan and arabinan.
  • Neryl diphosphate can also act as substrate.
Cross-references
BRENDA2.5.1.68
EC2PDB2.5.1.68
ExplorEnz2.5.1.68
PRIAM enzyme-specific profiles2.5.1.68
KEGG Ligand Database for Enzyme Nomenclature2.5.1.68
IUBMB Enzyme Nomenclature2.5.1.68
IntEnz2.5.1.68
MEDLINEFind literature relating to 2.5.1.68
MetaCyc2.5.1.68
UniProtKB/Swiss-Prot
Q7U0P8, ZFPP_MYCBO;  Q9CB36, ZFPP_MYCLE;  A0R2W4, ZFPP_MYCS2;  
P9WFF4, ZFPP_MYCTO;  P9WFF5, ZFPP_MYCTU;  Q47SS3, ZFPP_THEFY;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-