ENZYME entry: EC 2.5.1.88

Accepted Name
Trans,polycis-polyprenyl diphosphate synthase ((2Z,6E)-farnesyl diphosphate specific).
Reaction catalysed
(2Z,6E)-farnesyl diphosphate + n isopentenyl diphosphate <=> n diphosphate + trans,polycis-polyprenyl diphosphate (n = 9-11)
Comment(s)
  • Highest activity with (2Z,6E)-farnesyl diphosphate as allylic substrate.
  • Broad product specificity with the major product being dodecaprenyl diphosphate.
  • Synthesizes even C(70) prenyl diphosphate as the maximum chain-length product.
Cross-references
BRENDA2.5.1.88
EC2PDB2.5.1.88
ExplorEnz2.5.1.88
PRIAM enzyme-specific profiles2.5.1.88
KEGG Ligand Database for Enzyme Nomenclature2.5.1.88
IUBMB Enzyme Nomenclature2.5.1.88
IntEnz2.5.1.88
MEDLINEFind literature relating to 2.5.1.88
MetaCyc2.5.1.88
UniProtKB/Swiss-Prot
Q47RM6, DPDP_THEFY

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-