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ENZYME entry: EC 2.5.1.90

Accepted Name
All-trans-octaprenyl-diphosphate synthase.
Alternative Name(s)
Octaprenyl pyrophosphate synthetase.
Terpenyl pyrophosphate synthetase.
Trans-heptaprenyltranstransferase.
Trans-prenyltransferase.
Reaction catalysed
(2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate <=> 5 diphosphate + all-trans-octaprenyl diphosphate
Comment(s)
  • This enzyme catalyzes the condensation reactions resulting in the formation of all-trans-octaprenyl diphosphate, the isoprenoid side chain of ubiquinone-8 and menaquinone-8.
  • The enzyme adds five isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry.
Cross-references
BRENDA2.5.1.90
EC2PDB2.5.1.90
ExplorEnz2.5.1.90
PRIAM enzyme-specific profiles2.5.1.90
KEGG Ligand Database for Enzyme Nomenclature2.5.1.90
IUBMB Enzyme Nomenclature2.5.1.90
IntEnz2.5.1.90
MEDLINEFind literature relating to 2.5.1.90
MetaCyc2.5.1.90
UniProtKB/Swiss-Prot
P0AD57, ISPB_ECOLI;  P44916, ISPB_HAEIN;  P0AD58, ISPB_SHIFL;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-