ID   2.6.1.123
DE   4-amino-4-deoxychorismate synthase (2-amino-4-deoxychorismate-forming).
AN   ADCS.
AN   ADC synthase.
CA   chorismate + H2O + 2 L-glutamine = 4-amino-4-deoxychorismate +
CA   2 L-glutamate + NH4(+).
CC   -!- The enzyme, characterized from the bacterium Bacillus subtilis, is a
CC       heterodimer.
CC   -!- The PabA subunit acts successively on two molecules of L-glutamine,
CC       hydrolyzing each to L-glutamate and ammonia (cf. EC 3.5.1.2,
CC       glutaminase).
CC   -!- The ammonia molecules are channeled to the active site of PabB, which
CC       catalyzes the formation of 4-amino-4-deoxychorismate from chorismate
CC       in two steps, via the intermediate 2-amino-4-deoxychorismate. cf.
CC       EC 2.6.1.85.
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