ENZYME entry: EC 2.6.1.19
| Accepted Name |
| 4-aminobutyrate--2-oxoglutarate transaminase.
|
| Alternative Name(s) |
| 4-aminobutyrate aminotransferase. |
| Beta-alanine--oxoglutarate aminotransferase. |
| GABA transaminase. |
| Gamma-amino-N-butyrate transaminase. |
| Reaction catalysed |
| 4-aminobutanoate + 2-oxoglutarate <=> succinate semialdehyde + L-glutamate |
| Cofactor(s) |
| Pyridoxal 5'-phosphate.
|
| Comment(s) |
| Some preparations also act on beta-alanine, 5-aminopentanoate and
(R,S)-3-amino-2-methylpropanoate.
|
| Cross-references |
| PROSITE | PDOC00519 |
| BRENDA | 2.6.1.19 |
| EC2PDB | 2.6.1.19 |
| ExplorEnz | 2.6.1.19 |
| PRIAM enzyme-specific profiles | 2.6.1.19 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.6.1.19 |
| IUBMB Enzyme Nomenclature | 2.6.1.19 |
| IntEnz | 2.6.1.19 |
| MEDLINE | Find literature relating to 2.6.1.19 |
| MetaCyc | 2.6.1.19 |
| UniProtKB/Swiss-Prot |
| P14010, GABAT_EMENI; | O13837, GABAT_SCHPO; | P49604, GABAT_USTMA; |
| P17649, GABAT_YEAST; | P94427, GABT_BACSU; | Q9BGI0, GABT_BOVIN; |
| Q21217, GABT_CAEEL; | Q55FI1, GABT_DICDI; | P22256, GABT_ECOLI; |
| P80404, GABT_HUMAN; | P61922, GABT_MOUSE; | P63505, GABT_MYCBO; |
| P40829, GABT_MYCLE; | P63504, GABT_MYCTU; | P80147, GABT_PIG; |
| P50554, GABT_RAT; | P50457, PUUE_ECOLI; |
|
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