ENZYME entry: EC 2.6.1.22
| Accepted Name |
|---|
| (S)-3-amino-2-methylpropionate transaminase.
|
| Alternative Name(s) |
|---|
| (S)-3-amino-2-methylpropionate aminotransferase. |
| Beta-aminobutyric transaminase. |
| Beta-aminoisobutyrate-alpha-ketoglutarate transaminase. |
| L-3-aminoisobutyrate aminotransferase. |
| L-3-aminoisobutyrate transaminase. |
| L-3-aminoisobutyric aminotransferase. |
| L-AIBAT. |
| Reaction catalysed |
|---|
| (S)-3-amino-2-methylpropanoate + 2-oxoglutarate <=> 2-methyl-3-oxopropanoate + L-glutamate |
| Comment(s) |
|---|
- Also acts on beta-alanine and other omega-amino acids having carbon
chains between 2 and 5.
- The two enantiomers of the 2-methyl-3-oxopropanoate formed by the
enzyme interconvert by enolization, so that this enzyme, together
with EC 2.6.1.40, provide a route for interconversion of the
enantiomers of 3-amino-2-methylpropanoate.
|
| Cross-references |
|---|
| BRENDA | 2.6.1.22 |
| EC2PDB | 2.6.1.22 |
| ExplorEnz | 2.6.1.22 |
| PRIAM enzyme-specific profiles | 2.6.1.22 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.6.1.22 |
| IUBMB Enzyme Nomenclature | 2.6.1.22 |
| IntEnz | 2.6.1.22 |
| MEDLINE | Find literature relating to 2.6.1.22 |
| MetaCyc | 2.6.1.22 |
| UniProtKB/Swiss-Prot |
| P94427, GABT_BACSU; | Q9BGI0, GABT_BOVIN; | Q21217, GABT_CAEEL; |
| P22256, GABT_ECOLI; | P80404, GABT_HUMAN; | P61922, GABT_MOUSE; |
| P63505, GABT_MYCBO; | P40829, GABT_MYCLE; | P63504, GABT_MYCTU; |
| P80147, GABT_PIG; | P50554, GABT_RAT; |
|
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