ENZYME entry: EC 2.6.1.42

Accepted Name
Branched-chain-amino-acid transaminase.
Alternative Name(s)
Branched-chain amino acid aminotransferase.
Transaminase B.
Reaction catalysed
  • L-leucine + 2-oxoglutarate <=> 4-methyl-2-oxopentanoate + L-glutamate
  • L-isoleucine + 2-oxoglutarate <=> (S)-3-methyl-2-oxopentanoate + L-glutamate
  • L-valine + 2-oxoglutarate <=> 3-methyl-2-oxobutanoate + L-glutamate
Cofactor(s)
Pyridoxal 5'-phosphate.
Comment(s)
  • Also acts on L-isoleucine and L-valine.
  • Different from EC 2.6.1.66.
Cross-references
PROSITEPDOC00618
BRENDA2.6.1.42
EC2PDB2.6.1.42
ExplorEnz2.6.1.42
PRIAM enzyme-specific profiles2.6.1.42
KEGG Ligand Database for Enzyme Nomenclature2.6.1.42
IUBMB Enzyme Nomenclature2.6.1.42
IntEnz2.6.1.42
MEDLINEFind literature relating to 2.6.1.42
MetaCyc2.6.1.42
UniProtKB/Swiss-Prot
O14370, BCA1_SCHPO;  P38891, BCA1_YEAST;  P47176, BCA2_YEAST;  
Q93Y32, BCAT1_ARATH;  P54687, BCAT1_HUMAN;  P24288, BCAT1_MOUSE;  
P54690, BCAT1_RAT;  Q9GKM4, BCAT1_SHEEP;  Q9M439, BCAT2_ARATH;  
Q5EA40, BCAT2_BOVIN;  O15382, BCAT2_HUMAN;  O35855, BCAT2_MOUSE;  
O19098, BCAT2_PIG;  Q5REP0, BCAT2_PONAB;  O35854, BCAT2_RAT;  
Q9M401, BCAT3_ARATH;  Q9FYA6, BCAT5_ARATH;  Q9LPM9, BCAT6_ARATH;  
P54688, BCAT_CAEEL;  Q54N47, BCAT_DICDI;  A9UZ24, BCAT_MONBE;  
A7SLW1, BCAT_NEMVE;  O31461, ILVE1_BACSU;  P39576, ILVE2_BACSU;  
O67733, ILVE_AQUAE;  O29329, ILVE_ARCFU;  P0AB82, ILVE_ECO57;  
P0AB81, ILVE_ECOL6;  P0AB80, ILVE_ECOLI;  P54689, ILVE_HAEIN;  
Q9ZJF1, ILVE_HELPJ;  O26004, ILVE_HELPY;  Q58414, ILVE_METJA;  
O27481, ILVE_METTH;  O32954, ILVE_MYCLE;  A0R066, ILVE_MYCS2;  
Q10399, ILVE_MYCTU;  O86428, ILVE_PSEAE;  Q1RIJ2, ILVE_RICBR;  
Q92I26, ILVE_RICCN;  Q4ULR3, ILVE_RICFE;  O05970, ILVE_RICPR;  
Q9AKE5, ILVE_RICTY;  P0A1A6, ILVE_SALTI;  P0A1A5, ILVE_SALTY;  
Q5HIC1, ILVE_STAAC;  P63512, ILVE_STAAM;  P99138, ILVE_STAAN;  
Q6GJB4, ILVE_STAAR;  Q6GBT3, ILVE_STAAS;  P63513, ILVE_STAAW;  
Q5HRJ8, ILVE_STAEQ;  Q8CQ78, ILVE_STAES;  O86505, ILVE_STRCO;  
P54691, ILVE_SYNY3;  P74921, ILVE_THEMA;  Q9Y885, TOXF_COCCA;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.-.-
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