ENZYME entry: EC 2.6.1.5

Accepted Name
Tyrosine transaminase.
Alternative Name(s)
TyrAT.
Tyrosine aminotransferase.
Reaction catalysed
L-tyrosine + 2-oxoglutarate <=> 4-hydroxyphenylpyruvate + L-glutamate
Cofactor(s)
Pyridoxal 5'-phosphate.
Comment(s)
  • L-phenylalanine can act instead of L-tyrosine.
  • The mitochondrial enzyme may be identical with EC 2.6.1.1.
  • The three isoenzymic forms are interconverted by EC 3.4.22.32 and EC 3.4.22.33.
  • The enzyme can also catalyze the final step in the methionine-salvage pathway of Klebsiella pneumoniae.
Cross-references
PROSITEPDOC00098
BRENDA2.6.1.5
EC2PDB2.6.1.5
ExplorEnz2.6.1.5
PRIAM enzyme-specific profiles2.6.1.5
KEGG Ligand Database for Enzyme Nomenclature2.6.1.5
IUBMB Enzyme Nomenclature2.6.1.5
IntEnz2.6.1.5
MEDLINEFind literature relating to 2.6.1.5
MetaCyc2.6.1.5
UniProtKB/Swiss-Prot
Q58CZ9, ATTY_BOVIN;  Q54K95, ATTY_DICDI;  P17735, ATTY_HUMAN;  
Q8QZR1, ATTY_MOUSE;  P04694, ATTY_RAT;  Q02636, ATTY_RHIME;  
P33447, ATTY_TRYCR;  Q9LVY1, TAT_ARATH;  O85746, TYRB_KLEPN;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-