ENZYME entry: EC 2.6.1.7
| Accepted Name |
|---|
| Kynurenine--oxoglutarate transaminase.
|
| Alternative Name(s) |
|---|
| Kynurenine aminotransferase. |
| Kynurenine--oxoglutarate aminotransferase. |
| Reaction catalysed |
|---|
| L-kynurenine + 2-oxoglutarate <=> 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate |
| Cofactor(s) |
|---|
| Pyridoxal 5'-phosphate.
|
| Comment(s) |
|---|
- Also acts on 3-hydroxykynurenine.
- The product 4-(2-aminophenyl)-2,4-dioxobutanoate is converted into
kynurenate by a spontaneous reaction.
|
| Cross-references |
|---|
| BRENDA | 2.6.1.7 |
| EC2PDB | 2.6.1.7 |
| ExplorEnz | 2.6.1.7 |
| PRIAM enzyme-specific profiles | 2.6.1.7 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.6.1.7 |
| IUBMB Enzyme Nomenclature | 2.6.1.7 |
| IntEnz | 2.6.1.7 |
| MEDLINE | Find literature relating to 2.6.1.7 |
| MetaCyc | 2.6.1.7 |
| UniProtKB/Swiss-Prot |
| Q5E9N4, AADAT_BOVIN; | Q8N5Z0, AADAT_HUMAN; | Q9WVM8, AADAT_MOUSE; |
| Q64602, AADAT_RAT; | P38840, ARO9_YEAST; | P47039, BNA3_YEAST; |
| Q16773, KAT1_HUMAN; | Q8BTY1, KAT1_MOUSE; | Q08415, KAT1_RAT; |
| Q0P5G4, KAT3_BOVIN; | Q7T3E5, KAT3_DANRE; | Q6YP21, KAT3_HUMAN; |
| Q71RI9, KAT3_MOUSE; | Q58FK9, KAT3_RAT; | Q54KM6, KAT_DICDI; |
|
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