ENZYME entry: EC 2.7.1.11

Accepted Name
6-phosphofructokinase.
Alternative Name(s)
Phosphofructokinase I.
Phosphohexokinase.
Reaction catalysed
ATP + D-fructose 6-phosphate <=> ADP + D-fructose 1,6-bisphosphate
Comment(s)
  • D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.
  • UTP, CTP and ITP can act as donors.
  • Not identical with EC 2.7.1.105.
Cross-references
PROSITEPDOC00336 ; PDOC00504
BRENDA2.7.1.11
EC2PDB2.7.1.11
ExplorEnz2.7.1.11
PRIAM enzyme-specific profiles2.7.1.11
KEGG Ligand Database for Enzyme Nomenclature2.7.1.11
IUBMB Enzyme Nomenclature2.7.1.11
IntEnz2.7.1.11
MEDLINEFind literature relating to 2.7.1.11
MetaCyc2.7.1.11
UniProtKB/Swiss-Prot
Q9M0F9, K6PF1_ARATH;  Q9HGZ1, K6PF1_ASPOR;  Q8A8R5, K6PF1_BACTN;  
O94201, K6PF1_CANAX;  Q8XNH2, K6PF1_CLOPE;  P0A797, K6PF1_ECO57;  
Q8FBD0, K6PF1_ECOL6;  P0A796, K6PF1_ECOLI;  Q03215, K6PF1_KLULA;  
Q8YKG3, K6PF1_NOSS1;  Q92448, K6PF1_PICPA;  P0A798, K6PF1_SHIFL;  
O08333, K6PF1_STRCO;  P72830, K6PF1_SYNY3;  P21777, K6PF1_THET8;  
P59680, K6PF1_YARLI;  P16861, K6PF1_YEAST;  Q9FIK0, K6PF2_ARATH;  
Q9HGZ0, K6PF2_ASPOR;  Q8A624, K6PF2_BACTN;  O94200, K6PF2_CANAX;  
Q8XL57, K6PF2_CLOPE;  P06999, K6PF2_ECOLI;  Q03216, K6PF2_KLULA;  
Q8YVR1, K6PF2_NOSS1;  Q9L1L8, K6PF2_STRCO;  Q55988, K6PF2_SYNY3;  
P21778, K6PF2_THET8;  P16862, K6PF2_YEAST;  Q94AA4, K6PF3_ARATH;  
Q8A2E9, K6PF3_BACTN;  Q9FC99, K6PF3_STRCO;  Q9FKG3, K6PF4_ARATH;  
Q8VYN6, K6PF5_ARATH;  Q9M076, K6PF6_ARATH;  Q9C5J7, K6PF7_ARATH;  
A3N1C8, K6PF_ACTP2;  B3GY11, K6PF_ACTP7;  B0BQ64, K6PF_ACTPJ;  
A6VM63, K6PF_ACTSZ;  B6EMS4, K6PF_ALISL;  A6TVD3, K6PF_ALKMQ;  
A8MLY0, K6PF_ALKOO;  Q3M8N2, K6PF_ANAVT;  B7GGT1, K6PF_ANOFW;  
O67605, K6PF_AQUAE;  Q4W9B8, K6PF_ASPFU;  P78985, K6PF_ASPNG;  
A7Z7K6, K6PF_BACA2;  C3PAI8, K6PF_BACAA;  C3L8X8, K6PF_BACAC;  
A0RJJ6, K6PF_BACAH;  Q81KZ0, K6PF_BACAN;  B7JRX2, K6PF_BACC0;  
Q72ZD8, K6PF_BACC1;  B7IJZ8, K6PF_BACC2;  C1EUU3, K6PF_BACC3;  
B7HFB3, K6PF_BACC4;  B7HRN9, K6PF_BACC7;  Q4MVY3, K6PF_BACCE;  
A7GTP4, K6PF_BACCN;  B9J099, K6PF_BACCQ;  Q817F3, K6PF_BACCR;  
Q633J8, K6PF_BACCZ;  Q9K843, K6PF_BACHD;  Q6HCT3, K6PF_BACHK;  
Q65G82, K6PF_BACLD;  A8FG55, K6PF_BACP2;  Q5WEF6, K6PF_BACSK;  
O34529, K6PF_BACSU;  A9VJR1, K6PF_BACWK;  Q1LTT2, K6PF_BAUCH;  
Q7VRK9, K6PF_BLOFL;  Q0IIG5, K6PF_BOVIN;  C0Z7W7, K6PF_BREBN;  
B8D996, K6PF_BUCA5;  P57391, K6PF_BUCAI;  Q8K9N0, K6PF_BUCAP;  
B8D7J8, K6PF_BUCAT;  P59563, K6PF_BUCBP;  Q057P0, K6PF_BUCCC;  
Q27483, K6PF_CAEEL;  Q27543, K6PF_CALFI;  P52784, K6PF_CANFA;  
A9WCU2, K6PF_CHLAA;  B8GAA4, K6PF_CHLAD;  B9LHK4, K6PF_CHLSY;  
A8AL13, K6PF_CITK8;  O08308, K6PF_CLOAB;  A7FYW7, K6PF_CLOB1;  
C3KV06, K6PF_CLOB6;  B2UZX8, K6PF_CLOBA;  B2TQR6, K6PF_CLOBB;  
A5I798, K6PF_CLOBH;  C1FM55, K6PF_CLOBJ;  B1IFV9, K6PF_CLOBK;  
A7GIW9, K6PF_CLOBL;  B1L266, K6PF_CLOBM;  Q180P4, K6PF_CLOD6;  
A0PYC8, K6PF_CLONN;  Q890Z2, K6PF_CLOTE;  Q8RQN5, K6PF_COREF;  
Q8NR14, K6PF_CORGL;  Q83EH9, K6PF_COXBU;  A7MQ83, K6PF_CROS8;  
Q11RE2, K6PF_CYTH3;  Q9RWN1, K6PF_DEIRA;  P90521, K6PF_DICDI;  
P52034, K6PF_DROME;  A7ZUC9, K6PF_ECO24;  B7UNN6, K6PF_ECO27;  
B7MI48, K6PF_ECO45;  B7LA13, K6PF_ECO55;  B5YZ53, K6PF_ECO5E;  
B7NU91, K6PF_ECO7I;  B7N2Q7, K6PF_ECO81;  B7M6W7, K6PF_ECO8A;  
C5A083, K6PF_ECOBW;  B1XB82, K6PF_ECODH;  A8A720, K6PF_ECOHS;  
Q0TAE8, K6PF_ECOL5;  B1IVG3, K6PF_ECOLC;  B7NFL3, K6PF_ECOLU;  
B6I4Q8, K6PF_ECOSE;  B1LNL9, K6PF_ECOSM;  C5BC26, K6PF_EDWI9;  
A4WG81, K6PF_ENT38;  Q9Z6C3, K6PF_ENTCL;  Q836R3, K6PF_ENTFA;  
Q6CZ46, K6PF_ERWCT;  B2VF62, K6PF_ERWT9;  B7LVC9, K6PF_ESCF3;  
B0S230, K6PF_FINM2;  Q8RG98, K6PF_FUSNN;  Q5KWB1, K6PF_GEOKA;  
P00512, K6PF_GEOSE;  C5D663, K6PF_GEOSW;  Q27665, K6PF_HAECO;  
Q8GNC1, K6PF_HAEDU;  Q4QLS8, K6PF_HAEI8;  A5UD89, K6PF_HAEIE;  
P43863, K6PF_HAEIN;  B8F8G9, K6PF_HAEPS;  B8D1K5, K6PF_HALOH;  
C4K7E1, K6PF_HAMD5;  Q0I267, K6PF_HISS1;  B0UW05, K6PF_HISS2;  
Q867C9, K6PF_HORSE;  P08237, K6PF_HUMAN;  B5XZ40, K6PF_KLEP3;  
A6TGB8, K6PF_KLEP7;  Q5FKG6, K6PF_LACAC;  Q039I0, K6PF_LACC3;  
B3WE64, K6PF_LACCB;  P80019, K6PF_LACDE;  Q043V2, K6PF_LACGA;  
A8YV22, K6PF_LACH4;  Q74JM8, K6PF_LACJO;  Q07636, K6PF_LACLA;  
A2RKA2, K6PF_LACLM;  Q02YK5, K6PF_LACLS;  Q88VY1, K6PF_LACPL;  
Q1WTT3, K6PF_LACS1;  Q92BE4, K6PF_LISIN;  C1KVL8, K6PF_LISMC;  
Q71Z96, K6PF_LISMF;  B8DHH7, K6PF_LISMH;  Q8Y6W0, K6PF_LISMO;  
A0AJ20, K6PF_LISW6;  Q93LR4, K6PF_LYSSH;  B9E7A4, K6PF_MACCJ;  
Q60HD9, K6PF_MACFA;  Q65VM6, K6PF_MANSM;  P47857, K6PF_MOUSE;  
P65691, K6PF_MYCBO;  Q2SSQ6, K6PF_MYCCT;  P47457, K6PF_MYCGE;  
Q601D3, K6PF_MYCH2;  Q4A8Q3, K6PF_MYCH7;  Q4AAM2, K6PF_MYCHJ;  
O33106, K6PF_MYCLE;  Q6KHX0, K6PF_MYCMO;  Q8EVH2, K6PF_MYCPE;  
P75476, K6PF_MYCPN;  Q98PW8, K6PF_MYCPU;  P65690, K6PF_MYCTU;  
B2A6Y0, K6PF_NATTJ;  Q8EPD6, K6PF_OCEIH;  Q59214, K6PF_PAEMC;  
Q9CPH2, K6PF_PASMU;  C6DHK2, K6PF_PECCP;  Q03F74, K6PF_PEDPA;  
C0QQX4, K6PF_PERMH;  Q6LVK2, K6PF_PHOPR;  Q2HYU2, K6PF_PIG;  
Q5RAG9, K6PF_PONAB;  P00511, K6PF_RABIT;  P47858, K6PF_RAT;  
B5F0P6, K6PF_SALA4;  A9MI50, K6PF_SALAR;  Q57HF3, K6PF_SALCH;  
B5FPR2, K6PF_SALDC;  B5QWZ5, K6PF_SALEP;  B5RFA9, K6PF_SALG2;  
B4TCK0, K6PF_SALHS;  B4T049, K6PF_SALNS;  Q5PIR6, K6PF_SALPA;  
A9MZE7, K6PF_SALPB;  C0Q414, K6PF_SALPC;  B5BJI2, K6PF_SALPK;  
B4TPS6, K6PF_SALSV;  P65693, K6PF_SALTI;  P65692, K6PF_SALTY;  
Q27778, K6PF_SCHMA;  O42938, K6PF_SCHPO;  A8GLB0, K6PF_SERP5;  
B2TVQ8, K6PF_SHIB3;  Q31U74, K6PF_SHIBS;  Q32A80, K6PF_SHIDS;  
Q3YV62, K6PF_SHISS;  Q2NQX2, K6PF_SODGM;  P20275, K6PF_SPICI;  
A6U2G5, K6PF_STAA2;  A5ITM2, K6PF_STAA9;  Q2YTE2, K6PF_STAAB;  
Q5HF75, K6PF_STAAC;  A6QHN3, K6PF_STAAE;  P65694, K6PF_STAAM;  
P99165, K6PF_STAAN;  Q6GG08, K6PF_STAAR;  Q6G8M8, K6PF_STAAS;  
A8Z2L4, K6PF_STAAT;  P65695, K6PF_STAAW;  B9DN94, K6PF_STACT;  
Q5HNK6, K6PF_STAEQ;  Q8CS68, K6PF_STAES;  Q3K1E6, K6PF_STRA1;  
P65696, K6PF_STRA3;  P65697, K6PF_STRA5;  C0M8V6, K6PF_STRE4;  
B4U2M2, K6PF_STREM;  A8AXW1, K6PF_STRGC;  Q8DTX6, K6PF_STRMU;  
Q99ZD0, K6PF_STRP1;  Q04L24, K6PF_STRP2;  P0DD02, K6PF_STRP3;  
B5E3Z8, K6PF_STRP4;  Q5XBV2, K6PF_STRP6;  C1C6M8, K6PF_STRP7;  
Q8P0S6, K6PF_STRP8;  Q1JBF7, K6PF_STRPB;  Q1JLD9, K6PF_STRPC;  
Q1JGH6, K6PF_STRPD;  Q1J694, K6PF_STRPF;  A2RE65, K6PF_STRPG;  
B1IB66, K6PF_STRPI;  B8ZNU0, K6PF_STRPJ;  Q48T86, K6PF_STRPM;  
Q97RC6, K6PF_STRPN;  P0DD03, K6PF_STRPQ;  B2IP53, K6PF_STRPS;  
B5XLV6, K6PF_STRPZ;  Q8DQ85, K6PF_STRR6;  C0MGJ9, K6PF_STRS7;  
A3CM69, K6PF_STRSV;  A4VTS0, K6PF_STRSY;  Q03KB7, K6PF_STRTD;  
Q9L9E3, K6PF_STRTR;  B9DSA4, K6PF_STRU0;  C1CDP4, K6PF_STRZJ;  
C1CJY4, K6PF_STRZP;  C1CRZ7, K6PF_STRZT;  Q30T53, K6PF_SULDN;  
A6QAB4, K6PF_SULNB;  B2V7W7, K6PF_SULSY;  C5BNR1, K6PF_TERTT;  
Q8DJB1, K6PF_THEEB;  Q9WY52, K6PF_THEMA;  B9K6R9, K6PF_THENN;  
A5IKL2, K6PF_THEP1;  B0K7U7, K6PF_THEP3;  B0K6L2, K6PF_THEPX;  
B1L9U3, K6PF_THESQ;  Q72H98, K6PF_THET2;  Q8R914, K6PF_THETN;  
C4LEQ5, K6PF_TOLAT;  Q9PQV8, K6PF_UREPA;  A7MX59, K6PF_VIBCB;  
Q9KNP2, K6PF_VIBCH;  Q5E2B1, K6PF_VIBF1;  B5FBT1, K6PF_VIBFM;  
Q87KX0, K6PF_VIBPA;  Q8DCY1, K6PF_VIBVU;  Q7MGW6, K6PF_VIBVY;  
Q7M9C2, K6PF_WOLSU;  A1JHZ3, K6PF_YERE8;  A7FCW1, K6PF_YERP3;  
Q1C297, K6PF_YERPA;  B2JZA3, K6PF_YERPB;  Q8ZJL6, K6PF_YERPE;  
A9R6A3, K6PF_YERPG;  Q1CD33, K6PF_YERPN;  A4TSA7, K6PF_YERPP;  
Q66GA8, K6PF_YERPS;  B1JQU4, K6PF_YERPY;  A1A4J1, K6PL_BOVIN;  
P17858, K6PL_HUMAN;  P12382, K6PL_MOUSE;  Q5R7V5, K6PL_PONAB;  
P30835, K6PL_RAT;  Q01813, K6PP_HUMAN;  Q9WUA3, K6PP_MOUSE;  
Q5R636, K6PP_PONAB;  P47859, K6PP_RABIT;  P47860, K6PP_RAT;  
Q8H215, PFK_WHEAT;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.1.-
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