ENZYME entry: EC 2.7.1.119

Accepted Name
Hygromycin-B 7''-O-kinase.
Alternative Name(s)
APH(7'').
Hygromycin B phosphotransferase.
Hygromycin-B kinase.
Reaction catalysed
ATP + hygromycin B <=> ADP + 7''-O-phosphohygromycin B
Comment(s)
Phosphorylates the antibiotics hygromycin B, 1-N-hygromycin B and destomycin, but not hygromycin B2, at the 7''-hydroxy group in the destomic acid ring.
Cross-references
BRENDA	2.7.1.119
EC2PDB	2.7.1.119
ExplorEnz	2.7.1.119
PRIAM enzyme-specific profiles	2.7.1.119
KEGG Ligand Database for Enzyme Nomenclature	2.7.1.119
IUBMB Enzyme Nomenclature	2.7.1.119
IntEnz	2.7.1.119
MEDLINE	Find literature relating to 2.7.1.119
MetaCyc	2.7.1.119
UniProtKB/Swiss-Prot	P09979, KHYB_STRHY

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