ENZYME entry: EC 2.7.1.158

Accepted Name
Inositol-pentakisphosphate 2-kinase.
Alternative Name(s)
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase.
Inositol polyphosphate kinase.
Ins(1,3,4,5,6)P(5) 2-kinase.
IP5 2-kinase.
Reaction catalysed
ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate <=> ADP + 1D-myo-inositol hexakisphosphate
Comment(s)
  • The enzyme can also use Ins(1,4,5,6)P(4) and Ins(1,4,5)P(3) as substrate.
  • Inositol hexakisphosphate (phytate) accumulates in storage protein bodies during seed development and, when hydrolyzed, releases stored nutrients to the developing seedling before the plant is capable of absorbing nutrients from its environment.
Cross-references
BRENDA2.7.1.158
EC2PDB2.7.1.158
ExplorEnz2.7.1.158
PRIAM enzyme-specific profiles2.7.1.158
KEGG Ligand Database for Enzyme Nomenclature2.7.1.158
IUBMB Enzyme Nomenclature2.7.1.158
IntEnz2.7.1.158
MEDLINEFind literature relating to 2.7.1.158
MetaCyc2.7.1.158
UniProtKB/Swiss-Prot
Q75EW5, IPK1_ASHGO;  Q59KN8, IPK1_CANAL;  Q6FRN1, IPK1_CANGA;  
Q6BHL8, IPK1_DEBHA;  Q6CNG8, IPK1_KLULA;  B8AVX5, IPK1_ORYSI;  
Q7XQZ6, IPK1_ORYSJ;  Q9USK0, IPK1_SCHPO;  Q6C6Q7, IPK1_YARLI;  
Q06667, IPK1_YEAST;  Q93YN9, IPPK_ARATH;  P0CO35, IPPK_CRYNB;  
P0CO34, IPPK_CRYNJ;  Q4JL91, IPPK_DANRE;  Q9W2Q7, IPPK_DROME;  
Q9H8X2, IPPK_HUMAN;  Q6P1C1, IPPK_MOUSE;  Q5PXE9, IPPK_RAT;  
Q4P4C1, IPPK_USTMA;  

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