ID   2.7.1.159
DE   inositol-1,3,4-trisphosphate 5/6-kinase.
AN   inositol trisphosphate 5/6-kinase.
AN   Ins(1,3,4)P3 5/6-kinase.
AN   IP56K.
CA   (1) 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-
CA   tetrakisphosphate + ADP + H(+).
CA   (2) 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-
CA   tetrakisphosphate + ADP + H(+).
CC   -!- In humans, this enzyme, along with EC 2.7.1.127, EC 2.7.1.140 and
CC       EC 2.7.1.158 is involved in the production of inositol
CC       hexakisphosphate (InsP6).
CC   -!- InsP6 is involved in many cellular processes, including mRNA export
CC       from the nucleus.
CC   -!- Yeast do not have this enzyme, so produce InsP6 from Ins(1,4,5)P3 by
CC       the actions of EC 2.7.1.151 and EC 2.7.1.158.
CC   -!- The enzymes from animals and plants also have the activity of
CC       EC 2.7.1.134.
DR   Q9SBA5, ITPK1_ARATH;  P0C0T1, ITPK1_BOVIN;  Q5F480, ITPK1_CHICK;
DR   Q7ZU91, ITPK1_DANRE;  Q9XYQ1, ITPK1_ENTH1;  Q13572, ITPK1_HUMAN;
DR   Q84Y01, ITPK1_MAIZE;  Q8BYN3, ITPK1_MOUSE;  A2Z4C5, ITPK1_ORYSI;
DR   Q33BI9, ITPK1_ORYSJ;  A7X657, ITPK1_SOYBN;  Q7SY78, ITPK1_XENLA;
DR   O81893, ITPK2_ARATH;  B8AJL9, ITPK2_ORYSI;  Q10PL5, ITPK2_ORYSJ;
DR   A7X665, ITPK2_SOYBN;  Q9SUG3, ITPK3_ARATH;  B8AR41, ITPK3_ORYSI;
DR   Q75GI4, ITPK3_ORYSJ;  A7X672, ITPK3_SOYBN;  O80568, ITPK4_ARATH;
DR   A2X4M8, ITPK4_ORYSI;  Q6K7B8, ITPK4_ORYSJ;  A7X680, ITPK4_SOYBN;
DR   A0JJZ6, ITPK5_ORYSI;  Q7XBW0, ITPK5_ORYSJ;  B8BDK0, ITPK6_ORYSI;
DR   Q0J0B2, ITPK6_ORYSJ;
//