ENZYME entry: EC 2.7.1.162

Accepted Name
N-acetylhexosamine 1-kinase.
Alternative Name(s)
N-acetylgalactosamine/N-acetylglucosamine 1-kinase.
Reaction catalysed
ATP + N-acetyl-D-hexosamine <=> ADP + N-acetyl-alpha-D-hexosamine 1-phosphate
Cofactor(s)
Mg(2+).
Comment(s)
  • Involved in the lacto-N-biose I/galacto-N-biose degradation pathway in the probiotic bacterium Bifidobacterium longum.
  • Differs from EC 2.7.1.157 as it can phosphorylate both N-acetylgalactosamine and N-acetylglucosamine at similar rates.
  • Also has some activity with N-acetyl-D-mannosamine, D-talose and D-mannose as substrate.
  • ATP can be replaced by GTP or ITP but with decreased enzyme activity.
Cross-references
BRENDA2.7.1.162
EC2PDB2.7.1.162
ExplorEnz2.7.1.162
PRIAM enzyme-specific profiles2.7.1.162
KEGG Ligand Database for Enzyme Nomenclature2.7.1.162
IUBMB Enzyme Nomenclature2.7.1.162
IntEnz2.7.1.162
MEDLINEFind literature relating to 2.7.1.162
MetaCyc2.7.1.162
UniProtKB/Swiss-Prot
E8MF12, NAHK_BIFL2

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-