ENZYME entry: EC 2.7.1.164

Accepted Name
O-phosphoseryl-tRNA(Sec) kinase.
Alternative Name(s)
L-seryl-tRNA(Sec) kinase.
PSTK.
Reaction catalysed
ATP + L-seryl-tRNA(Sec) <=> ADP + O-phospho-L-seryl-tRNA(Sec)
Comment(s)
  • In archaea and eukarya selenocysteine formation is achieved by a two- step process: O-phosphoseryl-tRNA(Sec) kinase (PSTK) phosphorylates the endogenous L-seryl-tRNA(Sec) to O-phospho-L-seryl-tRNA(Sec), and then this misacylated amino acid-tRNA species is converted to L-selenocysteinyl-tRNA(Sec) by EC 2.9.1.2.
  • Formerly EC 2.7.1.n3.
Cross-references
BRENDA2.7.1.164
EC2PDB2.7.1.164
ExplorEnz2.7.1.164
PRIAM enzyme-specific profiles2.7.1.164
KEGG Ligand Database for Enzyme Nomenclature2.7.1.164
IUBMB Enzyme Nomenclature2.7.1.164
IntEnz2.7.1.164
MEDLINEFind literature relating to 2.7.1.164
MetaCyc2.7.1.164
UniProtKB/Swiss-Prot
Q8IV42, PSTK_HUMAN;  Q58933, PSTK_METJA;  Q8TUS5, PSTK_METKA;  
Q6LX62, PSTK_METMP;  Q8BP74, PSTK_MOUSE;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.1.-
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