To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https

ENZYME entry: EC 2.7.1.174

Accepted Name
Diacylglycerol kinase (CTP).
Alternative Name(s)
CTP-dependent diacylglycerol kinase.
DAG kinase.
Diacylglycerol kinase (CTP dependent).
Diglyceride kinase.
Reaction catalysed
CTP + 1,2-diacyl-sn-glycerol <=> CDP + 1,2-diacyl-sn-glycerol 3-phosphate
Cofactor(s)
Mg(2+) or Ca(2+).
Comment(s)
  • Involved in synthesis of membrane phospholipids and the neutral lipid triacylglycerol.
  • Unlike the diacylglycerol kinases from bacteria, plants, and animals (cf. EC 2.7.1.107), the enzyme from Saccharomyces cerevisiae utilizes CTP.
  • The enzyme can also use dCTP, but not ATP, GTP or UTP.
  • Formerly EC 2.7.1.n5.
Cross-references
BRENDA2.7.1.174
EC2PDB2.7.1.174
ExplorEnz2.7.1.174
PRIAM enzyme-specific profiles2.7.1.174
KEGG Ligand Database for Enzyme Nomenclature2.7.1.174
IUBMB Enzyme Nomenclature2.7.1.174
IntEnz2.7.1.174
MEDLINEFind literature relating to 2.7.1.174
MetaCyc2.7.1.174
UniProtKB/Swiss-Prot
Q753I3, DGK1_ASHGO;  P87170, DGK1_SCHPO;  Q12382, DGK1_YEAST;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-