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ENZYME entry: EC

Accepted Name
Protein-N(pi)-phosphohistidine--galactitol phosphotransferase.
Alternative Name(s)
Galactitol PTS permease.
Reaction catalysed
[Protein]-N(pi)-phospho-L-histidine + galactitol(Side 1) <=> [protein]-L-histidine + galactitol 1-phosphate(Side 2)
  • This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).
  • The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.
  • The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC
  • Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.
  • The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.
  • Formerly EC
PRIAM enzyme-specific profiles2.7.1.200
KEGG Ligand Database for Enzyme Nomenclature2.7.1.200
IUBMB Enzyme Nomenclature2.7.1.200
MEDLINEFind literature relating to
P69814, PTKA_ECO57;  P69813, PTKA_ECOL6;  P69828, PTKA_ECOLI;  
P0A436, PTKB_ECO57;  P0A435, PTKB_ECOL6;  P37188, PTKB_ECOLI;  

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