Due to improvement work scheduled on this server, some services may not be fully operational on Tuesday December 12 daytime (CEST).
To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https

ENZYME entry: EC 2.7.1.203

Accepted Name
Protein-N(pi)-phosphohistidine--D-glucosaminate phosphotransferase.
Alternative Name(s)
2-amino-2-deoxy-D-gluconate PTS permease.
Reaction catalysed
[Protein]-N(pi)-phospho-L-histidine + 2-amino-2-deoxy-D-gluconate(Side 1) <=> [protein]-L-histidine + 2-amino-2-deoxy-D-gluconate 6-phosphate(Side 2)
Comment(s)
  • This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).
  • The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.
  • The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.
  • Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.
  • The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.
  • Formerly EC 2.7.1.69.
Cross-references
PROSITEPDOC00795
BRENDA2.7.1.203
EC2PDB2.7.1.203
ExplorEnz2.7.1.203
PRIAM enzyme-specific profiles2.7.1.203
KEGG Ligand Database for Enzyme Nomenclature2.7.1.203
IUBMB Enzyme Nomenclature2.7.1.203
IntEnz2.7.1.203
MEDLINEFind literature relating to 2.7.1.203
MetaCyc2.7.1.203

View entry in original ENZYME format
View entry in raw text format (no links)
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-