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ENZYME entry: EC 18.104.22.168
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|Lactose PTS permease.|
|[Protein]-N(pi)-phospho-L-histidine + lactose(Side 1) <=> [protein]-L-histidine + lactose 6'-phosphate(Side 2)|
- This enzyme is a component (known as enzyme II) of a
phosphoenolpyruvate (PEP)-dependent, sugar transporting
phosphotransferase system (PTS).
- The system, which is found only in prokaryotes, simultaneously
transports its substrate from the periplasm or extracellular space
into the cytoplasm and phosphorylates it.
- The phosphate donor, which is shared among the different systems,
is a phospho-carrier protein of low molecular mass that has been
phosphorylated by EC 22.214.171.124.
- Enzyme II, on the other hand, is specific for a particular substrate,
although in some cases alternative substrates can be transported with
- The reaction involves a successive transfer of the phosphate group to
several amino acids within the enzyme before the final transfer to
- Formerly EC 126.96.36.199.
|PRIAM enzyme-specific profiles||188.8.131.52|
|KEGG Ligand Database for Enzyme Nomenclature||184.108.40.206|
|IUBMB Enzyme Nomenclature||220.127.116.11|
|MEDLINE||Find literature relating to 18.104.22.168|
|P11502, PTLA_LACCA; ||P23532, PTLA_LACLL; ||Q5HE14, PTLA_STAAC; |
|P0A0D3, PTLA_STAAM; ||P0A0D4, PTLA_STAAN; ||Q6GEN8, PTLA_STAAR; |
|Q6G7C3, PTLA_STAAS; ||P0A0D6, PTLA_STAAU; ||P0A0D5, PTLA_STAAW; |
|Q5HM39, PTLA_STAEQ; ||Q8CNF6, PTLA_STAES; ||P26426, PTLA_STRMU; |
|P24400, PTLCB_LACCA; ||P23531, PTLCB_LACLL; ||Q5HE15, PTLCB_STAAC; |
|Q931G6, PTLCB_STAAM; ||Q99S77, PTLCB_STAAN; ||Q6GEN9, PTLCB_STAAR; |
|Q6G7C4, PTLCB_STAAS; ||P11162, PTLCB_STAAU; ||Q7A092, PTLCB_STAAW; |
|Q5HM40, PTLCB_STAEQ; ||Q8CNF7, PTLCB_STAES; ||Q4L869, PTLCB_STAHJ; |
|P50976, PTLCB_STRMU; |
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