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ENZYME entry: EC 2.7.1.21

Accepted Name
Thymidine kinase.
Reaction catalysed
ATP + thymidine <=> ADP + thymidine 5'-phosphate
Comment(s)
  • Deoxyuridine can also act as acceptor.
  • dGTP can also act as donor.
  • The deoxypyrimidine kinase complex induced by Herpes simplex virus catalyzes this reaction as well as those of EC 2.7.1.114, EC 2.7.1.118, and EC 2.7.4.9.
  • Formerly EC 2.7.1.75.
Cross-references
PROSITEPDOC00524
BRENDA2.7.1.21
EC2PDB2.7.1.21
ExplorEnz2.7.1.21
PRIAM enzyme-specific profiles2.7.1.21
KEGG Ligand Database for Enzyme Nomenclature2.7.1.21
IUBMB Enzyme Nomenclature2.7.1.21
IntEnz2.7.1.21
MEDLINEFind literature relating to 2.7.1.21
MetaCyc2.7.1.21
UniProtKB/Swiss-Prot
Q7CXF9, KITH_AGRT5;  P33802, KITH_AHV1W;  Q21Q74, KITH_ALBFT;  
O36371, KITH_ALHV1;  P28852, KITH_AMEPV;  B7GMH4, KITH_ANOFW;  
P18555, KITH_ASFB7;  P0C8I3, KITH_ASFK5;  P0C8I4, KITH_ASFM2;  
P0C8I5, KITH_ASFP4;  P0C8I6, KITH_ASFWA;  Q2NIM1, KITH_AYWBP;  
A7Z9S5, KITH_BACA2;  C3P292, KITH_BACAA;  C3LFK4, KITH_BACAC;  
A0RLB6, KITH_BACAH;  Q81JX0, KITH_BACAN;  B7JHF2, KITH_BACC0;  
Q72XC1, KITH_BACC1;  B7IQY3, KITH_BACC2;  C1F0Q7, KITH_BACC3;  
B7HFM8, KITH_BACC4;  B7HY90, KITH_BACC7;  A7GV80, KITH_BACCN;  
B9IRW3, KITH_BACCQ;  Q814U0, KITH_BACCR;  Q630R8, KITH_BACCZ;  
Q5LHP5, KITH_BACFN;  Q64YL9, KITH_BACFR;  Q9K6F0, KITH_BACHD;  
Q6HAV3, KITH_BACHK;  Q65DU6, KITH_BACLD;  O52951, KITH_BACNA;  
A8FID5, KITH_BACP2;  Q5WB52, KITH_BACSK;  Q03221, KITH_BACSU;  
Q8A5G4, KITH_BACTN;  A6L1E7, KITH_BACV8;  A9VSC8, KITH_BACWK;  
Q6MHW4, KITH_BDEBA;  P24096, KITH_BHV16;  P24424, KITH_BHV1Q;  
P22649, KITH_BHV2H;  P36226, KITH_BHV5;  Q7VQZ6, KITH_BLOFL;  
Q492N1, KITH_BLOPB;  A5D7R8, KITH_BOVIN;  P13300, KITH_BPT4;  
Q05879, KITH_CBEPV;  Q05880, KITH_CFEPV;  P04047, KITH_CHICK;  
A9WGI6, KITH_CHLAA;  B8G6Y1, KITH_CHLAD;  B9LJ65, KITH_CHLSY;  
Q7NVK0, KITH_CHRVO;  Q97F65, KITH_CLOAB;  A7FQF9, KITH_CLOB1;  
C3KYH2, KITH_CLOB6;  A5HY32, KITH_CLOBH;  C1FQ94, KITH_CLOBJ;  
B1IE18, KITH_CLOBK;  A7G9N9, KITH_CLOBL;  B1KSQ8, KITH_CLOBM;  
Q898Y8, KITH_CLOTE;  Q483R5, KITH_COLP3;  B5Y8S5, KITH_COPPD;  
Q83A42, KITH_COXBU;  P09768, KITH_CRIGR;  C1D0Z6, KITH_DEIDV;  
Q9RSY5, KITH_DEIRA;  Q27564, KITH_DICDI;  B5YDB0, KITH_DICT6;  
B8E001, KITH_DICTD;  Q1HVD1, KITH_EBVA8;  P03177, KITH_EBVB9;  
Q3KSQ2, KITH_EBVG;  P0A3L9, KITH_ECO57;  Q8FHX4, KITH_ECOL6;  
P23331, KITH_ECOLI;  P69186, KITH_EHV1;  P69185, KITH_EHV1B;  
Q66624, KITH_EHV2;  P24425, KITH_EHV4;  Q18LE8, KITH_ELHVK;  
O96720, KITH_ENCCU;  Q831F5, KITH_ENTFA;  P13159, KITH_FHV1;  
P10052, KITH_FOWPN;  Q2A3U3, KITH_FRATH;  Q5NH50, KITH_FRATT;  
Q9E6P5, KITH_GAHVM;  P17653, KITH_GAHVR;  Q5KUH1, KITH_GEOKA;  
C5D9N8, KITH_GEOSW;  A4ITL0, KITH_GEOTN;  Q7VLH2, KITH_HAEDU;  
Q4QN19, KITH_HAEI8;  P44309, KITH_HAEIN;  B0R5S5, KITH_HALS3;  
Q9HPQ9, KITH_HALSA;  Q18J88, KITH_HALWD;  Q9QNF7, KITH_HHV1;  
P03176, KITH_HHV11;  P06478, KITH_HHV1C;  P08333, KITH_HHV1E;  
P17402, KITH_HHV1K;  P06479, KITH_HHV1S;  P04407, KITH_HHV23;  
P89446, KITH_HHV2H;  F5HB62, KITH_HHV8P;  P04183, KITH_HUMAN;  
P28855, KITH_ICHVA;  Q5QWC7, KITH_IDILO;  P23983, KITH_ILTVT;  
Q28M21, KITH_JANSC;  Q5FKZ1, KITH_LACAC;  Q74K26, KITH_LACJO;  
Q9CHX5, KITH_LACLA;  Q88UT1, KITH_LACPL;  Q38WJ3, KITH_LACSS;  
Q5X7B5, KITH_LEGPA;  Q5ZXU5, KITH_LEGPH;  Q5WYR3, KITH_LEGPL;  
Q927U9, KITH_LISIN;  Q71WN4, KITH_LISMF;  Q8Y4A7, KITH_LISMO;  
B9E8G2, KITH_MACCJ;  Q65RN9, KITH_MANSM;  P25987, KITH_MEHV1;  
P13157, KITH_MEHVF;  Q6F0I2, KITH_MESFL;  Q5UP25, KITH_MIMIV;  
P04363, KITH_MONPV;  P04184, KITH_MOUSE;  B3PM40, KITH_MYCA5;  
Q2SSX9, KITH_MYCCT;  Q8RLE0, KITH_MYCGA;  P47280, KITH_MYCGE;  
Q5ZZT0, KITH_MYCH2;  Q4A7B8, KITH_MYCH7;  Q4A977, KITH_MYCHJ;  
Q6KH30, KITH_MYCMO;  Q8VVL0, KITH_MYCMS;  Q8EU99, KITH_MYCPE;  
P75070, KITH_MYCPN;  Q9Q8N6, KITH_MYXVL;  P28851, KITH_MYXVU;  
Q2G5F0, KITH_NOVAD;  Q8EM59, KITH_OCEIH;  Q6YRB1, KITH_ONYPE;  
O81263, KITH_ORYSJ;  P57926, KITH_PASMU;  Q6D4R3, KITH_PECAS;  
Q7N457, KITH_PHOLL;  Q6LT81, KITH_PHOPR;  B2RJJ6, KITH_PORG3;  
Q7MVV7, KITH_PORGI;  Q6A8W6, KITH_PROAC;  Q3IBU5, KITH_PSEHT;  
Q6UDK9, KITH_PSHV1;  Q8ZV53, KITH_PYRAE;  Q90029, KITH_RACVI;  
P27158, KITH_RAT;  P07605, KITH_RFVKA;  Q2K5N6, KITH_RHIEC;  
Q98HR4, KITH_RHILO;  Q92N38, KITH_RHIME;  Q7UFR1, KITH_RHOBA;  
Q9ZIG2, KITH_RHOSI;  A7NI79, KITH_ROSCS;  A5UZV5, KITH_ROSS1;  
Q5LUY8, KITH_RUEPO;  Q57NR0, KITH_SALCH;  Q5PCT4, KITH_SALPA;  
Q2RZH4, KITH_SALRD;  Q8XFQ8, KITH_SALTI;  Q7CQF3, KITH_SALTY;  
Q8ECK0, KITH_SHEON;  P16600, KITH_SHEVK;  Q31ZS8, KITH_SHIBS;  
Q32GW8, KITH_SHIDS;  P0A3M0, KITH_SHIFL;  Q3Z0V3, KITH_SHISS;  
P04408, KITH_SHV1;  P21293, KITH_SHV21;  Q2FF09, KITH_STAA3;  
Q2YUN4, KITH_STAAB;  Q5HE81, KITH_STAAC;  P65230, KITH_STAAM;  
P65231, KITH_STAAN;  Q6GEV6, KITH_STAAR;  Q6G7J1, KITH_STAAS;  
Q8NVG5, KITH_STAAW;  Q5HMA3, KITH_STAEQ;  Q8CRM9, KITH_STAES;  
Q4L800, KITH_STAHJ;  Q49Z66, KITH_STAS1;  Q3K118, KITH_STRA1;  
Q8E5C2, KITH_STRA3;  Q8DZM3, KITH_STRA5;  Q82KI9, KITH_STRAW;  
O50519, KITH_STRCO;  P47848, KITH_STRGC;  Q8DU63, KITH_STRMU;  
Q99ZP6, KITH_STRP1;  P0DB96, KITH_STRP3;  Q5XC70, KITH_STRP6;  
Q8P126, KITH_STRP8;  Q48TL1, KITH_STRPM;  Q97R22, KITH_STRPN;  
P0DB97, KITH_STRPQ;  Q8DPZ6, KITH_STRR6;  Q5M0B8, KITH_STRT1;  
Q5M4W5, KITH_STRT2;  P27363, KITH_SUHVN;  P23335, KITH_SWPVK;  
Q5JGT7, KITH_THEKO;  A8F7B3, KITH_THELT;  Q9WYN2, KITH_THEMA;  
A5IK18, KITH_THEP1;  B0K7G9, KITH_THEP3;  B0K1F4, KITH_THEPX;  
B1L989, KITH_THESQ;  Q8RDA1, KITH_THETN;  B1AJN5, KITH_UREP2;  
Q9PPP5, KITH_UREPA;  B5ZCA9, KITH_UREU1;  O57203, KITH_VACCA;  
P68564, KITH_VACCC;  Q9JFB7, KITH_VACCT;  P68563, KITH_VACCW;  
P04364, KITH_VAR67;  Q9KST9, KITH_VIBCH;  Q5E4F2, KITH_VIBF1;  
Q87QJ8, KITH_VIBPA;  Q8D8R2, KITH_VIBVU;  Q7MLR4, KITH_VIBVY;  
P09250, KITH_VZVD;  P0C0E6, KITH_VZVO;  Q8PEQ8, KITH_XANAC;  
Q3BM98, KITH_XANC5;  Q4UNV0, KITH_XANC8;  Q8P3C8, KITH_XANCP;  
Q2P902, KITH_XANOM;  Q5H6C5, KITH_XANOR;  Q8ZEJ1, KITH_YERPE;  
Q66AM8, KITH_YERPS;  Q90033, KITH_YMTV5;  Q5NQ29, KITH_ZYMMO;  
O00142, KITM_HUMAN;  Q9N0C5, KITM_MACFA;  Q9R088, KITM_MOUSE;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-