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ENZYME

ENZYME entry: EC 2.7.1.235

Accepted Name
lipopolysaccharide core heptose(I) kinase
Reaction catalysed
an L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ATP <=> ADP + an L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + H(+)
Comment(s)
The enzyme catalyzes the phosphorylation of L-glycero-D-manno-heptose I (the first heptose added to the lipid, Hep I) in the biosynthesis of the inner core oligosaccharide of the lipopolysaccharide (endotoxin) of some Gram-negative bacteria.
Cross-references
BRENDA2.7.1.235
EC2PDB2.7.1.235
ExplorEnz2.7.1.235
PRIAM enzyme-specific profiles2.7.1.235
KEGG Ligand Database for Enzyme Nomenclature2.7.1.235
IUBMB Enzyme Nomenclature2.7.1.235
IntEnz2.7.1.235
MEDLINEFind literature relating to 2.7.1.235
MetaCyc2.7.1.235
Rhea expert-curated reactions2.7.1.235
UniProtKB/Swiss-Prot
P25741, WAAP_ECOLIQ9R9D6, WAAP_ECOLXQ9HUF7, WAAP_PSEAE
Q06995, WAAP_SALTY

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.1.-
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