ENZYME entry: EC 2.7.1.235
Accepted Name | |||||
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lipopolysaccharide core heptose(I) kinase | |||||
Reaction catalysed | |||||
an L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ATP <=> ADP + an L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + H(+) | |||||
Comment(s) | |||||
The enzyme catalyzes the phosphorylation of L-glycero-D-manno-heptose I (the first heptose added to the lipid, Hep I) in the biosynthesis of the inner core oligosaccharide of the lipopolysaccharide (endotoxin) of some Gram-negative bacteria. | |||||
Cross-references | |||||
BRENDA | 2.7.1.235 | ||||
EC2PDB | 2.7.1.235 | ||||
ExplorEnz | 2.7.1.235 | ||||
PRIAM enzyme-specific profiles | 2.7.1.235 | ||||
KEGG Ligand Database for Enzyme Nomenclature | 2.7.1.235 | ||||
IUBMB Enzyme Nomenclature | 2.7.1.235 | ||||
IntEnz | 2.7.1.235 | ||||
MEDLINE | Find literature relating to 2.7.1.235 | ||||
MetaCyc | 2.7.1.235 | ||||
Rhea expert-curated reactions | 2.7.1.235 | ||||
UniProtKB/Swiss-Prot |
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