ENZYME entry: EC 2.7.1.26

Accepted Name
Riboflavin kinase.
Alternative Name(s)
Flavokinase.
RFK.
Reaction catalysed
ATP + riboflavin <=> ADP + FMN
Cofactor(s)
Magnesium or zinc or manganese.
Comment(s)
  • The cofactors FMN and FAD participate in numerous processes in all organisms, including mitochondrial electron transport, photosynthesis, fatty-acid oxidation, and metabolism of vitamin B(6), vitamin B12 and folates.
  • While monofunctional riboflavin kinase is found in eukaryotes, some bacteria have a bifunctional enzyme that exhibits both this activity and that of EC 2.7.7.2.
  • In Bacillus subtilis, ATP can be replaced by other phosphate donors but with decreasing enzyme activity in the order ATP > dATP > CTP > UTP.
Cross-references
BRENDA2.7.1.26
EC2PDB2.7.1.26
ExplorEnz2.7.1.26
PRIAM enzyme-specific profiles2.7.1.26
KEGG Ligand Database for Enzyme Nomenclature2.7.1.26
IUBMB Enzyme Nomenclature2.7.1.26
IntEnz2.7.1.26
MEDLINEFind literature relating to 2.7.1.26
MetaCyc2.7.1.26
UniProtKB/Swiss-Prot
Q7NBZ0, MNMA_MYCGA;  P54575, RIBC_BACSU;  P57250, RIBF_BUCAI;  
Q8K9Z1, RIBF_BUCAP;  Q59263, RIBF_CORAM;  P0AG42, RIBF_ECO57;  
P0AG41, RIBF_ECOL6;  P0AG40, RIBF_ECOLI;  A4IT50, RIBF_GEOTN;  
P44957, RIBF_HAEIN;  P47391, RIBF_MYCGE;  P75587, RIBF_MYCPN;  
P22990, RIBF_PSEFL;  O84990, RIBF_RHOOP;  P0AG43, RIBF_SHIFL;  
P73651, RIBF_SYNY3;  P94465, RIBR_BACSU;  Q75DY2, RIFK_ASHGO;  
A1C603, RIFK_ASPCL;  Q4WHD2, RIFK_ASPFU;  A2QFH1, RIFK_ASPNC;  
Q2UMM4, RIFK_ASPOR;  Q0CHR1, RIFK_ASPTN;  Q6FM49, RIFK_CANGA;  
P0C5D9, RIFK_CHAGB;  O76206, RIFK_DROME;  Q5AW61, RIFK_EMENI;  
Q969G6, RIFK_HUMAN;  Q6CT57, RIFK_KLULA;  A5E1A0, RIFK_LODEL;  
A4QQ05, RIFK_MAGO7;  Q8CFV9, RIFK_MOUSE;  A1DG00, RIFK_NEOFI;  
Q6M923, RIFK_NEUCR;  A5DAH9, RIFK_PICGU;  A3M0C9, RIFK_PICST;  
O74866, RIFK_SCHPO;  Q6CG11, RIFK_YARLI;  Q03778, RIFK_YEAST;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-