ENZYME entry: EC 2.7.1.40

Accepted Name
Pyruvate kinase.
Alternative Name(s)
Phosphoenol transphosphorylase.
Phosphoenolpyruvate kinase.
Reaction catalysed
ATP + pyruvate <=> ADP + phosphoenolpyruvate
Comment(s)
  • UTP, GTP, CTP, ITP and dATP can also act as donors.
  • Also phosphorylates hydroxylamine and fluoride in the presence of CO(2).
Cross-references
PROSITEPDOC00101
BRENDA2.7.1.40
EC2PDB2.7.1.40
ExplorEnz2.7.1.40
PRIAM enzyme-specific profiles2.7.1.40
KEGG Ligand Database for Enzyme Nomenclature2.7.1.40
IUBMB Enzyme Nomenclature2.7.1.40
IntEnz2.7.1.40
MEDLINEFind literature relating to 2.7.1.40
MetaCyc2.7.1.40
UniProtKB/Swiss-Prot
Q43117, KPYA_RICCO;  Q40545, KPYA_TOBAC;  O65595, KPYC_ARATH;  
P22200, KPYC_SOLTU;  Q42806, KPYC_SOYBN;  Q42954, KPYC_TOBAC;  
P55964, KPYG_RICCO;  Q40546, KPYG_TOBAC;  P70789, KPYK1_AGRVI;  
Q6FIS9, KPYK1_CANGA;  P0AD62, KPYK1_ECO57;  P0AD61, KPYK1_ECOLI;  
O30853, KPYK1_PHOLE;  Q8Z6K2, KPYK1_SALTI;  P77983, KPYK1_SALTY;  
Q55863, KPYK1_SYNY3;  P30615, KPYK1_TRYBB;  P00549, KPYK1_YEAST;  
Q44473, KPYK2_AGRVI;  Q6FV12, KPYK2_CANGA;  P21599, KPYK2_ECOLI;  
Q8ZNW0, KPYK2_SALTY;  P73534, KPYK2_SYNY3;  P30616, KPYK2_TRYBB;  
P52489, KPYK2_YEAST;  Q9YEU2, KPYK_AERPE;  O94122, KPYK_AGABI;  
Q759A9, KPYK_ASHGO;  Q12669, KPYK_ASPNG;  P51181, KPYK_BACLI;  
P80885, KPYK_BACSU;  O51323, KPYK_BORBU;  P57404, KPYK_BUCAI;  
Q8K9M3, KPYK_BUCAP;  Q89AI8, KPYK_BUCBP;  P46614, KPYK_CANAL;  
Q9PK61, KPYK_CHLMU;  Q9Z984, KPYK_CHLPN;  B0B7Q0, KPYK_CHLT2;  
P0CE21, KPYK_CHLTR;  O08309, KPYK_CLOAB;  P81344, KPYK_CLOPA;  
Q46289, KPYK_CLOPE;  Q8FP04, KPYK_COREF;  Q46078, KPYK_CORGL;  
Q6BS75, KPYK_DEBHA;  Q54RF5, KPYK_DICDI;  O62619, KPYK_DROME;  
O44006, KPYK_EIMTE;  P22360, KPYK_EMENI;  Q8SQP0, KPYK_ENCCU;  
Q02499, KPYK_GEOSE;  P43924, KPYK_HAEIN;  P31865, KPYK_HYPJE;  
Q875M9, KPYK_KLULA;  P34038, KPYK_LACDE;  Q875S4, KPYK_LACK1;  
Q07637, KPYK_LACLA;  Q04668, KPYK_LEIBR;  Q27686, KPYK_LEIME;  
O05118, KPYK_METEA;  Q57572, KPYK_METJA;  P47458, KPYK_MYCGE;  
P94939, KPYK_MYCIT;  P78031, KPYK_MYCPN;  P9WKE4, KPYK_MYCTO;  
P9WKE5, KPYK_MYCTU;  Q875Z9, KPYK_NAUCC;  Q7RVA8, KPYK_NEUCR;  
Q8ZYE0, KPYK_PYRAE;  Q10208, KPYK_SCHPO;  P19680, KPYK_SPICI;  
P51182, KPYK_SPOPS;  Q2FG40, KPYK_STAA3;  Q2FXM9, KPYK_STAA8;  
Q2YTE3, KPYK_STAAB;  Q5HF76, KPYK_STAAC;  Q99TG5, KPYK_STAAM;  
Q7A559, KPYK_STAAN;  Q6GG09, KPYK_STAAR;  Q6G8M9, KPYK_STAAS;  
Q7A0N4, KPYK_STAAW;  Q5HNK7, KPYK_STAEQ;  Q8CS69, KPYK_STAES;  
Q4L739, KPYK_STAHJ;  Q49YC7, KPYK_STAS1;  P32044, KPYK_THEAC;  
Q56301, KPYK_THELI;  Q9WY51, KPYK_THEMA;  Q27788, KPYK_TRYBO;  
P30614, KPYK_YARLI;  P00548, KPYM_CHICK;  P11979, KPYM_FELCA;  
P14618, KPYM_HUMAN;  P52480, KPYM_MOUSE;  Q5NVN0, KPYM_PONAB;  
P11974, KPYM_RABIT;  P11980, KPYM_RAT;  Q92122, KPYM_XENLA;  
Q29536, KPYR_CANFA;  P30613, KPYR_HUMAN;  P53657, KPYR_MOUSE;  
P12928, KPYR_RAT;  Q9LIK0, PKP1_ARATH;  Q9FLW9, PKP2_ARATH;  
Q93Z53, PKP3_ARATH;  Q9M3B6, PKP4_ARATH;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.1.-
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