ID   2.7.1.68
DE   1-phosphatidylinositol-4-phosphate 5-kinase.
AN   diphosphoinositide kinase.
AN   phosphatidylinositol-4-phosphate 5-kinase.
AN   phosphatidylinositol 4-phosphate kinase.
AN   PIP kinase.
AN   PtdIns(4)P-5-kinase.
AN   type I PIP kinase.
CA   a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP =
CA   a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) +
CA   ADP + H(+).
CC   -!- This enzyme can also phosphorylate PtdIns3P in the 4-position,
CC       and PtdIns, PtdIns3P and PtdIns(3,4)P2 in the 5-position in vitro,
CC       but to a lesser extent.
CC   -!- The last of these reactions occurs in vivo and is physiologically
CC       relevant.
DR   O13853, ITS3_SCHPO ;  P38994, MSS4_YEAST ;  Q99755, PI51A_HUMAN;
DR   P70182, PI51A_MOUSE;  D3ZSI8, PI51A_RAT  ;  Q5ZJ58, PI51B_CHICK;
DR   O14986, PI51B_HUMAN;  P70181, PI51B_MOUSE;  Q5CZZ9, PI51B_RAT  ;
DR   O60331, PI51C_HUMAN;  O70161, PI51C_MOUSE;  Q5I6B8, PI51C_RAT  ;
DR   Q8I239, PI51N_PLAF7;  Q56YP2, PI5K1_ARATH;  Q9W2R3, PI5K1_DROME;
DR   Q6EX42, PI5K1_ORYSJ;  Q8L796, PI5K2_ARATH;  O48709, PI5K3_ARATH;
DR   Q9M1K2, PI5K4_ARATH;  Q9SLG9, PI5K5_ARATH;  Q9SFB8, PI5K6_ARATH;
DR   Q9SUI2, PI5K7_ARATH;  Q8RY89, PI5K8_ARATH;  Q8L850, PI5K9_ARATH;
DR   Q9LMN1, PI5KA_ARATH;  Q9M149, PI5KB_ARATH;  Q17QS4, PI5L1_BOVIN;
DR   Q5T9C9, PI5L1_HUMAN;
//