ID   2.7.11.11
DE   cAMP-dependent protein kinase.
AN   PKA.
AN   PKA C.
AN   Protein kinase A.
CA   ATP + a protein = ADP + a phosphoprotein.
CC   -!- cAMP is required to activate this enzyme.
CC   -!- The inactive holoenzyme of cAMP-dependent protein kinase is a
CC       tetramer composed of two regulatory (R) and two catalytic (C)
CC       subunits.
CC   -!- cAMP causes the dissociation of the inactive holoenzyme into a dimer
CC       of regulatory subunits bound to four cAMP molecules and two free
CC       monomeric catalytic subunits (i.e. R(2)C(2) + 4 cAMP = R(2)(cAMP)(4)
CC       + 2 C).
CC   -!- Formerly EC 2.7.1.37.
PR   PROSITE; PDOC00100;
DR   P06244, KAPA_YEAST ;  P40376, KAPB_SCHPO ;  P06245, KAPB_YEAST ;
DR   P00517, KAPCA_BOVIN;  Q8MJ44, KAPCA_CANFA;  P25321, KAPCA_CRIGR;
DR   P17612, KAPCA_HUMAN;  P05132, KAPCA_MOUSE;  P36887, KAPCA_PIG  ;
DR   P27791, KAPCA_RAT  ;  Q9MZD9, KAPCA_SHEEP;  P05131, KAPCB_BOVIN;
DR   P68180, KAPCB_CRIGR;  P22694, KAPCB_HUMAN;  P68181, KAPCB_MOUSE;
DR   P05383, KAPCB_PIG  ;  P68182, KAPCB_RAT  ;  P22612, KAPCG_HUMAN;
DR   O62846, KAPCG_MACMU;  P49673, KAPC_ASCSU ;  P21137, KAPC_CAEEL ;
DR   P34099, KAPC_DICDI ;  P12370, KAPC_DROME ;  Q8SRK8, KAPC_ENCCU ;
DR   P05986, KAPC_YEAST ;
//