ENZYME entry: EC 2.7.4.14

Accepted Name
UMP/CMP kinase.
Alternative Name(s)
CMP kinase.
Cytidine monophosphate kinase.
Cytidylate kinase.
dCMP kinase.
Deoxycytidine kinase.
Deoxycytidylate kinase.
UMP-CMP kinase.
Uridine monophosphate-cytidine monophosphate phosphotransferase.
Reaction catalysed
Comment(s)
  • This eukaryotic enzyme is a bifunctional enzyme that catalyzes the phosphorylation of both CMP and UMP with similar efficiency.
  • dCMP can also act as acceptor.
  • Different from the monofunctional prokaryotic enzymes EC 2.7.4.25, CMP kinase and EC 2.7.4.22, UMP kinase.
  • This eukaryotic enzyme is a bifunctional enzyme that catalyzes the phosphorylation of both CMP and UMP with similar efficiency.
  • dCMP can also act as acceptor.
  • Different from the monofunctional prokaryotic enzymes EC 2.7.4.25 and EC 2.7.4.22.
  • Formerly EC 2.7.4.5.
Cross-references
PROSITEPDOC00104
BRENDA2.7.4.14
EC2PDB2.7.4.14
ExplorEnz2.7.4.14
PRIAM enzyme-specific profiles2.7.4.14
KEGG Ligand Database for Enzyme Nomenclature2.7.4.14
IUBMB Enzyme Nomenclature2.7.4.14
IntEnz2.7.4.14
MEDLINEFind literature relating to 2.7.4.14
MetaCyc2.7.4.14
UniProtKB/Swiss-Prot
Q5EBM0, CMPK2_HUMAN;  Q3U5Q7, CMPK2_MOUSE;  Q2KIW9, KCY_BOVIN;  
Q5ZKE7, KCY_CHICK;  Q7ZWE9, KCY_DANRE;  P20425, KCY_DICDI;  
P30085, KCY_HUMAN;  Q9DBP5, KCY_MOUSE;  Q29561, KCY_PIG;  
Q4KM73, KCY_RAT;  Q7ZX23, KCY_XENLA;  Q28H12, KCY_XENTR;  
B0C6S1, PANCY_ACAM1;  Q3MEJ8, PANCY_ANAVT;  Q7NJM6, PANCY_GLOVI;  
Q8YSZ3, PANCY_NOSS1;  A3PF80, PANCY_PROM0;  A2C536, PANCY_PROM1;  
A8G795, PANCY_PROM2;  A2CBX2, PANCY_PROM3;  Q318F2, PANCY_PROM9;  
Q7V9S8, PANCY_PROMA;  Q7V583, PANCY_PROMM;  Q7UZR6, PANCY_PROMP;  
A2BTH1, PANCY_PROMS;  Q46IM3, PANCY_PROMT;  Q31P38, PANCY_SYNE7;  
Q2JRH9, PANCY_SYNJA;  Q2JJ30, PANCY_SYNJB;  Q5N530, PANCY_SYNP6;  
A5GIY5, PANCY_SYNPW;  Q7U4P0, PANCY_SYNPX;  A5GVR3, PANCY_SYNR3;  
Q0ICW2, PANCY_SYNS3;  Q3AUV1, PANCY_SYNS9;  Q3AMJ0, PANCY_SYNSC;  
Q55074, PANCY_SYNY3;  Q8DG73, PANCY_THEEB;  Q110U9, PANCY_TRIEI;  
O04905, UMPK_ARATH;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.4.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
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