ENZYME entry: EC 2.7.7.31

Accepted Name
DNA nucleotidylexotransferase.
Alternative Name(s)
Terminal addition enzyme.
Terminal deoxynucleotidyltransferase.
Terminal deoxyribonucleotidyltransferase.
Terminal transferase.
Reaction catalysed
Deoxynucleoside triphosphate + DNA(n) <=> diphosphate + DNA(n+1)
Comment(s)
  • Catalyzes template-independent extension of the 3'-end of a DNA strand by one nucleotide at a time.
  • Cannot initiate a chain de novo.
  • Nucleoside may be ribo- or deoxyribo-.
Cross-references
PROSITEPDOC00452
BRENDA2.7.7.31
EC2PDB2.7.7.31
ExplorEnz2.7.7.31
PRIAM enzyme-specific profiles2.7.7.31
KEGG Ligand Database for Enzyme Nomenclature2.7.7.31
IUBMB Enzyme Nomenclature2.7.7.31
IntEnz2.7.7.31
MEDLINEFind literature relating to 2.7.7.31
MetaCyc2.7.7.31
UniProtKB/Swiss-Prot
O57486, TDT_AMBME;  P06526, TDT_BOVIN;  P36195, TDT_CHICK;  
A4PCD4, TDT_EULMA;  P04053, TDT_HUMAN;  O02789, TDT_MONDO;  
P09838, TDT_MOUSE;  Q92089, TDT_ONCMY;  P42118, TDT_XENLA;  

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