ENZYME entry: EC 2.7.7.46
| Accepted Name |
|---|
| Gentamicin 2''-nucleotidyltransferase.
|
| Alternative Name(s) |
|---|
| 2''-aminoglycoside nucleotidyltransferase. |
| Reaction catalysed |
|---|
| Nucleoside triphosphate + gentamicin <=> diphosphate + 2''-nucleotidylgentamicin |
| Comment(s) |
|---|
- ATP, dATP, CTP, ITP and GTP can act as donors.
- Kanamycin, tobramycin and sisomicin can also act as acceptors.
- The nucleotidyl residue is transferred to the 2-hydroxy group of the
3-amino-3-deoxy-D-glucose moiety in the antibiotic.
|
| Cross-references |
|---|
| BRENDA | 2.7.7.46 |
| EC2PDB | 2.7.7.46 |
| ExplorEnz | 2.7.7.46 |
| PRIAM enzyme-specific profiles | 2.7.7.46 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.7.7.46 |
| IUBMB Enzyme Nomenclature | 2.7.7.46 |
| IntEnz | 2.7.7.46 |
| MEDLINE | Find literature relating to 2.7.7.46 |
| MetaCyc | 2.7.7.46 |
| UniProtKB/Swiss-Prot |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot
entries referenced
in this entry, with possibility to download in different formats, align etc.
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.7.7.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-