ENZYME entry: EC 2.7.7.64
| Accepted Name |
|---|
| UTP-monosaccharide-1-phosphate uridylyltransferase.
|
| Alternative Name(s) |
|---|
| UDP-sugar pyrophosphorylase. |
| USP. |
| Reaction catalysed |
|---|
| UTP + a monosaccharide 1-phosphate <=> diphosphate + UDP-monosaccharide |
| Cofactor(s) |
|---|
| Manganese or magnesium.
|
| Comment(s) |
|---|
- The reaction can occur in either direction and it has been postulated
that MgUTP and Mg-diphosphate are the actual substrates.
- Catalyzes the formation of UDP-Glc, UDP-Gal, UDP-GlcA, UDP-L-Ara and
UDP-Xyl, showing broad substrate specificity toward monosaccharide
1-phosphates.
- Mannose 1-phosphate, L-fucose 1-phosphate and glucose 6-phosphate are
not substrates and UTP cannot be replaced by other nucleotide
triphosphates.
|
| Cross-references |
|---|
| BRENDA | 2.7.7.64 |
| EC2PDB | 2.7.7.64 |
| ExplorEnz | 2.7.7.64 |
| PRIAM enzyme-specific profiles | 2.7.7.64 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.7.7.64 |
| IUBMB Enzyme Nomenclature | 2.7.7.64 |
| IntEnz | 2.7.7.64 |
| MEDLINE | Find literature relating to 2.7.7.64 |
| MetaCyc | 2.7.7.64 |
| UniProtKB/Swiss-Prot |
|
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