ID   2.7.7.65
DE   Diguanylate cyclase.
AN   DGC.
CA   2 GTP = 2 diphosphate + cyclic di-3',5'-guanylate.
CF   Magnesium; Manganese.
CC   -!- Can be activated by BeF3, a phosphoryl mimic, which results in
CC       dimerization.
CC   -!- Dimerization is required but is not sufficient for diguanylate-
CC       cyclase activity.
CC   -!- Cyclic di-3',5'-guanylate is an intracellular signaling molecule that
CC       controls motility and adhesion in bacterial cells; it was first
CC       identified as having a positive allosteric effect on EC 2.4.1.12.
DR   P0AAP1, ADRA_ECOLI ;  P0AA89, DOSC_ECOLI ;  B8GZM2, PLED_CAUCN ;
DR   Q9A5I5, PLED_CAUCR ;  P75908, YCDT_ECOLI ;  P77302, YDAM_ECOLI ;
DR   P0AA90, YDDV_ECO57 ;  Q320T0, YDDV_SHIBS ;  Q0T466, YDDV_SHIF8 ;
DR   Q83KV7, YDDV_SHIFL ;  Q3Z1N3, YDDV_SHISS ;  P31129, YDEH_ECOLI ;
DR   P76237, YEAJ_ECOLI ;  P76245, YEAP_ECOLI ;  P76330, YEDQ_ECOLI ;
DR   P38097, YEGE_ECOLI ;  P46139, YFIN_ECOLI ;
//