ID 2.7.7.84 DE 2'-5' oligoadenylate synthase. CA 3 ATP = 5'-triphosphoadenylyl-(2'->5')-adenylyl-(2'->5')-adenosine + CA 2 diphosphate. CC -!- The enzyme is activated by binding to double-stranded RNA. CC -!- The resulting product binds to and activates RNase L, which CC subsequently degrades the RNA. CC -!- Oligoadenylates of chain lengths 2, 4 and 5 are also produced. CC -!- The dimer does not have any known biological activity. DR P11928, OAS1A_MOUSE; Q05961, OAS1A_RAT ; P00973, OAS1_HUMAN ; DR Q29599, OAS1_PIG ; F1N3B8, OAS2_BOVIN ; P29728, OAS2_HUMAN ; DR E9Q9A9, OAS2_MOUSE ; Q5MYU0, OAS2_RAT ; Q9Y6K5, OAS3_HUMAN ; DR Q8VI93, OAS3_MOUSE ; Q5MYT7, OAS3_RAT ; Q9Z2F2, OASL2_MOUSE; DR Q5MYT9, OASL2_RAT ; //