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ENZYME

ENZYME entry: EC 2.7.7.86

Accepted Name
cyclic GMP-AMP synthase
Reaction catalysed
ATP + GTP <=> 2',3'-cGAMP + 2 diphosphate
Comment(s)
Cyclic Gp(2'-5')Ap(3'-5') is a signaling molecule in mammalian cells that triggers the production of type I interferons and other cytokines.
Cross-references
BRENDA2.7.7.86
EC2PDB2.7.7.86
ExplorEnz2.7.7.86
PRIAM enzyme-specific profiles2.7.7.86
KEGG Ligand Database for Enzyme Nomenclature2.7.7.86
IUBMB Enzyme Nomenclature2.7.7.86
IntEnz2.7.7.86
MEDLINEFind literature relating to 2.7.7.86
MetaCyc2.7.7.86
Rhea expert-curated reactions2.7.7.86
UniProtKB/Swiss-Prot
E1BGN7, CGAS_BOVINQ8N884, CGAS_HUMANQ8C6L5, CGAS_MOUSE
A7SFB5, CGAS_NEMVEI3LM39, CGAS_PIGA8DYP7, CGLR2_DROME
D6WI29, CGLR_TRICA

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.7.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
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