ENZYME entry: EC 2.7.8.12

Accepted Name
Teichoic acid poly(glycerol phosphate) polymerase.
Alternative Name(s)
Poly(glycerol phosphate) polymerase.
Tag polymerase.
Teichoic acid glycerol transferase.
Teichoic-acid synthase.
Reaction catalysed
n CDP-glycerol + 4-O-((2R)-glycerophospho)-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> n CMP + 4-O-(((2R)-glycerophospho)n-(2R)-glycerophospho)-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
Comment(s)
  • Involved in the biosynthesis of poly glycerol phosphate teichoic acids in bacterial cell walls.
  • This enzyme adds 30-50 glycerol units to the linker molecule, but only after it has been primed with the first glycerol unit by EC 2.7.8.44.
  • Cf. EC 2.7.8.45.
Cross-references
BRENDA2.7.8.12
EC2PDB2.7.8.12
ExplorEnz2.7.8.12
PRIAM enzyme-specific profiles2.7.8.12
KEGG Ligand Database for Enzyme Nomenclature2.7.8.12
IUBMB Enzyme Nomenclature2.7.8.12
IntEnz2.7.8.12
MEDLINEFind literature relating to 2.7.8.12
MetaCyc2.7.8.12
UniProtKB/Swiss-Prot
P13485, TAGF_BACSU;  Q5HLM5, TAGF_STAEQ;  Q8RKI5, TARF_BACPZ;  

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