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ENZYME

ENZYME entry: EC 2.7.8.14

PURL: https://purl.expasy.org/enzyme/EC/2.7.8.14
Accepted Name
CDP-ribitol ribitolphosphotransferase
Alternative Name(s)
polyribitol phosphate polymerase
teichoate synthase
teichoic-acid synthase
Reaction catalysed
4-O-[di(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CDP-L-ribitol = 4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CMP + n H(+)
Comment(s)
  • Involved in the biosynthesis of poly ribitol phosphate teichoic acids in the cell wall of the bacterium Staphylococcus aureus.
  • This enzyme adds around 40 ribitol units to the linker molecule.
  • Formerly EC 2.4.1.55.
Cross-references
Rhea expert-curated reactions2.7.8.14
ExplorEnz2.7.8.14
IUBMB Enzyme Nomenclature2.7.8.14
UniProtKB/Swiss-Prot
Q2G1C2, TARK_STAA8Q2G1B8, TARL_STAA8
BRENDA2.7.8.14
MetaCyc2.7.8.14
KEGG Ligand Database for Enzyme Nomenclature2.7.8.14
EC2PDB2.7.8.14
MEDLINEFind literature relating to 2.7.8.14

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