ID   2.7.8.48
DE   ceramide phosphoethanolamine synthase.
AN   CPE synthase.
CA   an N-acyl-sphingoid base + CDP-ethanolamine = an N-acyl-sphingoid
CA   1-phosphoethanolamine + CMP + H(+).
CC   -!- The enzyme, studied from the fly Drosophila melanogaster,
CC       has homologs among the invertebrates, but not in other animal phyla.
CC   -!- Its product, ceramide phosphoethanolamine, is synthesized as the main
CC       sphingolipid in cell membranes of arthropods, such as Drosophila and
CC       Musca, and is common in worms, bees, spiders, and scorpions.
CC   -!- It has also been reported in deep-sea mussels and some sea snails,
CC       as well as protozoans and oomycetes.
CC   -!- The enzyme requires a Mn(II) cofactor.
CC   -!- Formerly EC 2.7.8.n3.
DR   O77475, CPESY_DROME;
//