ID   2.8.2.31
DE   petromyzonol sulfotransferase.
AN   PZ-SULT.
CA   3'-phosphoadenylyl sulfate + 5alpha-cholane-3alpha,7alpha,12alpha,24-
CA   tetrol = 3alpha,7alpha,12alpha-trihydroxy-5alpha-cholan-24-yl sulfate +
CA   adenosine 3',5'-bisphosphate + H(+).
CC   -!- The enzyme from the lamprey Petromyzon marinus can also use the
CC       corresponding 3-ketone as a substrate.
CC   -!- It is stereoselective (5alpha-cholane) and regioselective, exhibiting
CC       a preference for an hydroxy group at C-24.
CC   -!- The enzyme is inactive when allocholic acid, which has a carboxy
CC       group at C-24, is used as a substrate.
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