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ENZYME

ENZYME entry: EC 2.8.3.22

Accepted Name
succinyl-CoA--L-malate CoA-transferase
Reaction catalysed
  • (S)-malate + succinyl-CoA <=> (S)-malyl-CoA + succinate
  • (3S)-citramalate + succinyl-CoA <=> (3S)-citramalyl-CoA + succinate
Comment(s)
  • The enzyme, purified from the bacterium Chloroflexus aurantiacus, can also accept itaconate as acceptor, with lower efficiency.
  • It is part of the 3-hydroxypropanoate cycle for carbon assimilation.
Cross-references
BRENDA2.8.3.22
EC2PDB2.8.3.22
ExplorEnz2.8.3.22
PRIAM enzyme-specific profiles2.8.3.22
KEGG Ligand Database for Enzyme Nomenclature2.8.3.22
IUBMB Enzyme Nomenclature2.8.3.22
IntEnz2.8.3.22
MEDLINEFind literature relating to 2.8.3.22
MetaCyc2.8.3.22
Rhea expert-curated reactions2.8.3.22
UniProtKB/Swiss-Prot
A9WC40, SMTA_CHLAAQ1KLK1, SMTA_CHLAUA9WC39, SMTB_CHLAA
Q1KLK0, SMTB_CHLAU

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