Due to scheduled maintenance work, this service may not be available on Monday January 22nd between 08.00 am and 9.00 am CEST.
To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https

ENZYME entry: EC

Accepted Name
Bile acid CoA-transferase.
Alternative Name(s)
Bile acid coenzyme A transferase.
Reaction catalysed
  • Lithocholoyl-CoA + cholate <=> lithocholate + choloyl-CoA
  • Deoxycholoyl-CoA + cholate <=> deoxycholate + choloyl-CoA
  • The enzyme, characterized from the gut bacterium Clostridium scindens, catalyzes the last step in bile acid 7-alpha- dehydroxylation, the removal of the CoA moiety from the products.
  • By using a transferase rather than hydrolase, the bacteria conserve the thioester bond energy, saving ATP molecules.
  • The enzyme has a broad substrate specificity and can use multiple acceptors, including allocholate, ursodeoxycholate, and beta- muricholate.
  • Formerly EC
PRIAM enzyme-specific profiles2.8.3.25
KEGG Ligand Database for Enzyme Nomenclature2.8.3.25
IUBMB Enzyme Nomenclature2.8.3.25
MEDLINEFind literature relating to

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.8.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.8.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-