ID 3.1.1.51 DE phorbol-diester hydrolase. AN diacylphorbate 12-hydrolase. CA H2O + phorbol 12,13-dibutanoate = butanoate + H(+) + phorbol CA 13-butanoate. CC -!- Hydrolyzes the 12-ester bond in a variety of 12,13-diacylphorbols CC (phorbol is a diterpenoid). CC -!- This reaction inactivates tumor promoter 12-O-tetradecanoylphorbol- CC 13-acetate from croton oil. //